Trunk sway in mildly disabled multiple sclerosis patients with and without balance impairment

Findling, Oliver; Sellner, Johann; Meier, Niklaus; Allum, John H J; Vibert, Dominique; Lienert, Carmen; Mattle, Heinrich P (2011). Trunk sway in mildly disabled multiple sclerosis patients with and without balance impairment. Experimental brain research, 213(4), pp. 363-70. Berlin: Springer 10.1007/s00221-011-2795-8

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Multiple sclerosis (MS) causes a broad range of neurological symptoms. Most common is poor balance control. However, knowledge of deficient balance control in mildly affected MS patients who are complaining of balance impairment but have normal clinical balance tests (CBT) is limited. This knowledge might provide insights into the normal and pathophysiological mechanisms underlying stance and gait. We analysed differences in trunk sway between mildly disabled MS patients with and without subjective balance impairment (SBI), all with normal CBT. The sway was measured for a battery of stance and gait balance tests (static and dynamic posturography) and compared to that of age- and sex-matched healthy subjects. Eight of 21 patients (38%) with an Expanded Disability Status Scale of 1.0-3.0 complained of SBI during daily activities. For standing on both legs with eyes closed on a normal and on a foam surface, patients in the no SBI group showed significant differences in the range of trunk roll (lateral) sway angle and velocity, compared to normal persons. Patients in the SBI group had significantly greater lateral sway than the no SBI group, and sway was also greater than normal in the pitch (anterior-posterior) direction. Sway for one-legged stance on foam was also greater in the SBI group compared to the no SBI and normal groups. We found a specific laterally directed impairment of balance in all patients, consistent with a deficit in proprioceptive processing, which was greater in the SBI group than in the no SBI group. This finding most likely explains the subjective symptoms of imbalance in patients with MS with normal CBT.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurology
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)

UniBE Contributor:

Findling, Oliver; Meier, Niklaus and Mattle, Heinrich

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0014-4819

Publisher:

Springer

Funders:

[4] Swiss National Science Foundation
[7] Swiss Multiple Sclerosis Society

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:14

Last Modified:

06 Dec 2013 13:23

Publisher DOI:

10.1007/s00221-011-2795-8

PubMed ID:

21773798

Web of Science ID:

000294173700002

URI:

https://boris.unibe.ch/id/eprint/3351 (FactScience: 207011)

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