Characterization of microfluidic systems with Doppler optical coherence tomography

Carrion, L; Hamel, E; Leblanc-Hotte, A; Boudoux, C; Guenat, O; Maciejko, R (2009). Characterization of microfluidic systems with Doppler optical coherence tomography. In: Photonics North 2009. Quebec, Canada. 24-27 May 2009. 10.1117/12.839798

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Doppler Optical Coherence Tomography (DOCT) is a biomedical imaging technique that allows simultaneous structural imaging and flow monitoring inside biological tissues and materials with spatial resolution in the micrometer scale. It has recently been applied to the characterization of microfluidic systems. Structural and flow imaging of novel microfluidics platforms for cytotoxicologic applications were obtained with a real-time, Near Infrared Spectral Domain DOCT system. Characteristics such as flow homogeneity in the chamber, which is one of the most important parameters for cell culture, are investigated. OCT and DOCT images were used to monitor flow inside a specific platform that is based on microchannel division for a better flow homogeneity. In particular, the evolution of flow profile at the transition between the microchannel structure and the chamber is studied.

Item Type:	Conference or Workshop Item (Paper)
Division/Institute:	04 Faculty of Medicine > Pre-clinic Human Medicine > Institute for Surgical Technology & Biomechanics ISTB [discontinued]
UniBE Contributor:	Guenat, Olivier Thierry
ISBN:	9780819476685
Series:	SPIE Proceedings
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 15:24
Last Modified:	05 Dec 2022 14:26
Publisher DOI:	10.1117/12.839798
URI:	https://boris.unibe.ch/id/eprint/37895 (FactScience: 212187)