Guenat, Olivier Thierry

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Ferrari, Dario; Sengupta, Arunima; Heo, Lyong; Pethö, Laszlo; Michler, Johann; Geiser, Thomas; de Jesus Perez, Vinicio A; Kuebler, Wolfgang M; Zeinali, Soheila; Guenat, Olivier T (2023). Effects of biomechanical and biochemical stimuli on angio- and vasculogenesis in a complex microvasculature-on-chip. iScience, 26(3), p. 106198. Elsevier 10.1016/j.isci.2023.106198

Sengupta, Arunima; Dorn, Aurélien; Jamshidi, Mohammad; Schwob, Magali; Hassan, Widad; De Maddalena, Lea Lara; Hugi, Andreas; Stucki, Andreas O.; Dorn, Patrick; Marti, Thomas M.; Wisser, Oliver; Stucki, Janick D.; Krebs, Tobias; Hobi, Nina; Guenat, Olivier T. (2023). A multiplex inhalation platform to model in situ like aerosol delivery in a breathing lung-on-chip. Frontiers in Pharmacology, 14 Frontiers 10.3389/fphar.2023.1114739


Bakirci, Ezgi; Guenat, O T; Ahmad, S S; Gantenbein, B (2022). Tissue engineering approaches for the repair and regeneration of the anterior cruciate ligament: towards 3D bioprinted ACL-on-chip. European cells & materials eCM, 44, pp. 21-42. University of Wales 10.22203/eCM.v044a02

Sengupta, Arunima; Roldan, Nuria; Kiener, Mirjam; Froment, Laurène; Raggi, Giulia; Imler, Theo; de Maddalena, Lea; Rapet, Aude; May, Tobias; Carius, Patrick; Schneider-Daum, Nicole; Lehr, Claus-Michael; Kruithof-de Julio, Marianna; Geiser, Thomas; Marti, Thomas; Stucki, Janick D.; Hobi, Nina; Guenat, Olivier T (2022). A New Immortalized Human Alveolar Epithelial Cell Model to Study Lung Injury and Toxicity on a Breathing Lung-On-Chip System. Frontiers in toxicology, 4(840606), pp. 1-18. Frontiers Media S.A. 10.3389/ftox.2022.840606

Candarlioglu, Pelin L; Dal Negro, Gianni; Hughes, David; Balkwill, Frances; Harris, Kate; Screen, Hazel; Morgan, Hywel; David, Rhiannon; Beken, Sonja; Guenat, Olivier; Rowan, Wendy; Amour, Augustin (2022). Organ-on-a-chip: current gaps and future directions. Biochemical Society transactions, 50(2), pp. 665-673. Portland Press 10.1042/BST20200661

van der Does, Anne M.; Guenat, Olivier T.; Geiser, Thomas; Hiemstra, Peter S. (2022). Chapter 8 Lung-on-Chip. In: Westergren-Thorsson, Gunilla; Rolandsson Enes, Sara (eds.) 3D Lung Models for Regenerating Lung Tissue (pp. 133-151). Elsevier 10.1016/B978-0-323-90871-9.00001-2

Guenat, Olivier; Zamprogno, Pauline (2022). Ein biologisches Lungenmodell mit Forschungspotenzial. Biospektrum, 28(2), pp. 152-154. Springer 10.1007/s12268-022-1731-8


Zamprogno, Pauline; Thoma, Giuditta; Cencen, Veronika; Ferrari, Dario; Putz, Barbara; Michler, Johann; Fantner, Georg E.; Guenat, Olivier T. (2021). Mechanical properties of soft biological membranes for organ-on-a-chip assessed by bulge test and AFM. ACS biomaterials science & engineering, 7(7), pp. 2990-2997. American Chemical Society 10.1021/acsbiomaterials.0c00515

Zeinali, Soheila; Thompson, Emily K; Gerhardt, Holger; Geiser, Thomas; Guenat, Olivier Thierry T. (2021). Remodeling of an in vitro microvessel exposed to cyclic mechanical stretch. APL bioengineering, 5(2), 026102. AIP Publishing 10.1063/5.0010159

Kiener, Mirjam; Roldan, Nuria; Machahua, Carlos; Sengupta, Arunima; Geiser, Thomas; Guenat, Olivier Thierry; Funke-Chambour, Manuela; Hobi, Nina; Kruithof-de Julio, Marianna (2021). Human-Based Advanced in vitro Approaches to Investigate Lung Fibrosis and Pulmonary Effects of COVID-19. Frontiers in medicine, 8(644678), p. 644678. Frontiers 10.3389/fmed.2021.644678

Tang, Ye; Kurth, Felix; Burr, Loïc; Petropoulos, Konstantinos; Migliorelli, Davide; Guenat, Olivier T.; Generelli, Silvia (2021). Nanocellulose aerogel inserts for quantitative lateral flow immunoassays. Biosensors & bioelectronics, 192(113491), pp. 1-9. Elsevier 10.1016/j.bios.2021.113491

Zamprogno, Pauline; Wüthrich, Simon; Achenbach, Sven; Thoma, Giuditta; Stucki, Janick D.; Hobi, Nina; Schneider-Daum, Nicole; Lehr, klaus-michael; Huwer, Hanno; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier T. (2021). Second-generation lung-on-a-chip with an array of stretchable alveoli made with a biological membrane. Communications biology, 4(1), p. 168. Springer Nature 10.1038/s42003-021-01695-0


Guenat, Olivier T.; Geiser, Thomas; Berthiaume, François (2020). Clinically Relevant Tissue Scale Responses as New Readouts from Organs-on-a-Chip for Precision Medicine. Annual review of analytical chemistry, 13(1), pp. 111-133. Annual Reviews 10.1146/annurev-anchem-061318-114919

Wang, Limei; Dorn, Patrick; Zeinali, Soheila; Froment, Laurène; Berezowska, Sabina; Kocher, Gregor; Alves, Marco P; Brügger, Melanie; Esteves, Blandina I.O.; Blank, Fabian; Wotzkow, Carlos; Steiner, Selina; Amacker, Mario; Peng, Ren-Wang; Marti, Thomas; Guenat, Olivier Thierry; Bode, Peter Karl; Moehrlen, Ueli; Schmid, Ralph and Hall, Sean (2020). CD90+CD146+ identifies a pulmonary mesenchymal cell subtype with both immune modulatory and perivascular-like function in postnatal human lung. American journal of physiology - lung cellular and molecular physiology, 318(4), L813-L830. American Physiological Society 10.1152/ajplung.00146.2019

Tang, Ye; Petropoulos, Konstantinos; Kurth, Felix; Hui, Gao; Migliorelli, Davide; Guenat, Olivier; Generelli, Silvia (2020). Screen-Printed Glucose Sensors Modified with Cellulose Nanocrystals (CNCs) for Cell Culture Monitoring. Biosensors, 10(9), p. 125. MDPI 10.3390/bios10090125


Artzy-Schnirman, Arbel; Hobi, Nina; Schneider-Daum, Nicole; Guenat, Olivier T.; Lehr, Claus-Michael; Sznitman, Josué (2019). Advanced in vitro lung-on-chip platforms for inhalation assays: From prospect to pipeline. European journal of pharmaceutics and biopharmaceutics, 144, pp. 11-17. Elsevier 10.1016/j.ejpb.2019.09.006

Zamprogno, Pauline; Wüthrich, Simon; Achenbach, Sven; Stucki, Janick D.; Hobi, Nina; Schneider-Daum, Nicole; Lehr, Claus-Michael; Huwer, Hanno; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier T. (2019). Second-generation lung-on-a-chip array with a stretchable biological membrane (bioRxiv). Cold Spring Harbor Laboratory 10.1101/608919

Felder, Marcel Christian; Trueeb, Bettina; Stucki, Andreas Oliver; Borcard, Sarah; Stucki, Janick Daniel; Schnyder, Bruno; Geiser, Thomas; Guenat, Olivier Thierry (2019). Impaired Wound Healing of Alveolar Lung Epithelial Cells in a Breathing Lung-on-a-chip. Frontiers in Bioengineering and Biotechnology, 7(3), p. 3. Frontiers Media 10.3389/fbioe.2019.00003


Zeinali, Soheila; Bichsel, Colette A.; Hobi, Nina; Funke, Manuela; Marti, Thomas M.; Schmid, Ralph A.; Guenat, Olivier T.; Geiser, Thomas (2018). Human microvasculature-on-a chip: anti-neovasculogenic effect of nintedanib in vitro. Angiogenesis, 21(4), pp. 861-871. Springer Netherlands 10.1007/s10456-018-9631-8

Mermoud, Yves; Felder, Marcel Christian; Stucki, Janick; Stucki, Andreas; Guenat, Olivier Thierry (2018). Microimpedance tomography system to monitor cell activity and membrane movements in a breathing lung-on-chip. Sensors and Actuators B: Chemical, 255(3), pp. 3647-3653. Elsevier 10.1016/j.snb.2017.09.192

Guenat, Olivier Thierry; Berthiaume, François (2018). Incorporating mechanical strain in organs-on-a-chip: Lung and skin. Biomicrofluidics, 12(4), 042207. American Institute of Physics 10.1063/1.5024895

Sfriso, Riccardo; Zhang, Shengye; Bichsel, Colette Andrea; Steck, Oliver Thomas; Despont, Alain; Guenat, Olivier Thierry; Rieben, Robert (2018). 3D artificial round section micro-vessels to investigate endothelial cells under physiological flow conditions. Scientific Reports, 8(1), p. 5898. Nature Publishing Group 10.1038/s41598-018-24273-7

Stucki, Janick; Hobi, Nina; Galimov, Artur; Stucki, Andreas; Schneider-Daum, Nicole; Lehr, Claus-Michael; Huwer, Hanno; Frick, Manfred; Funke-Chambour, Manuela; Geiser, Thomas; Guenat, Olivier Thierry (2018). Medium throughput breathing human primary cell alveolus-on-chip model. Scientific Reports, 8(1), p. 14359. Nature Publishing Group 10.1038/s41598-018-32523-x


Bakirci, Ezgi; Guenat, Olivier Thierry; Hugi, Andreas; Ahmad, Sufian; Kohl, Sandro; Gantenbein, Benjamin (2017). Optimization of 3D printed hydrogels with primary cells for tissue engineering (Unpublished). In: AOSPine Masters Symposium-Novel and Emerging Technologies in Translational Medicine. Bern. 22 September 2017.

Bichsel, Colette; Wang, Limei; Froment, Laurène; Berezowska, Sabina Anna; Müller, Stefan Jürg; Dorn, Patrick; Marti, Thomas M.; Peng, Ren-Wang; Geiser, Thomas; Schmid, Ralph A.; Guenat, Olivier Thierry; Hall, Sean (2017). Increased PD-L1 expression and IL-6 secretion characterize human lung tumor-derived perivascular-like cells that promote vascular leakage in a perfusable microvasculature model. Scientific Reports, 7(1), p. 10636. Nature Publishing Group 10.1038/s41598-017-09928-1


la Cour, Jakob B.; Generelli, Silvia; Barbe, Laurent; Guenat, Olivier Thierry (2016). Low-cost disposable ALT electrochemical microsensors for in-vitro hepatotoxic assessment. Sensors and Actuators B: Chemical, 228, pp. 360-365. Elsevier 10.1016/j.snb.2016.01.008


Wick, P.; Chortarea, S.; Guenat, Olivier Thierry; Roesslein, M.; Stucki, Janick; Hirn, S.; Petri-Fink, A.; Rothen-Rutishauser, B. (2015). In vitro-ex vivo model systems for nanosafety assessment. European Journal of Nanomedicine, 7(3), pp. 169-179. De Gruyter 10.1515/ejnm-2014-0049

Bichsel, Colette Andrea; Hall, Sean; Schmid, Ralph; Guenat, Olivier Thierry; Geiser, Thomas (2015). Primary human lung pericytes support and stabilize in-vitro perfusable microvessels. Tissue engineering. Part A, 21(15-16), p. 2166. Mary Ann Liebert 10.1089/ten.TEA.2014.0545

Stucki, Janick; Guenat, Olivier Thierry (2015). A microfluidic bubble trap and oscillator. Lab on a chip, 15(23), pp. 4393-4397. Royal Society of Chemistry 10.1039/C5LC00592B

Stucki, Andreas; Stucki, Janick Daniel; Hall, Sean; Felder, Marcel Christian; Mermoud, Yves; Schmid, Ralph; Geiser, Thomas; Guenat, Olivier Thierry (2015). A lung-on-chip array with an integrated bio-inspired respiration mechanism. Lab on a chip, 15(5), pp. 1302-1310. Royal Society of Chemistry 10.1039/C4LC01252F

Ruppen, Janine; Wildhaber, Franziska Daniela; Strub, Christoph; Hall, Sean; Geiser, Thomas; Schmid, Ralph; Guenat, Olivier Thierry (2015). Towards personalized medicine: Chemosensitivity assays of patient lung cancer cell spheroids in a perfused microfluidic platform. Lab on a chip, 15(14), pp. 3076-3085. Royal Society of Chemistry 10.1039/C5LC00454C


Felder, Marcel; Stucki, Andreas; Stucki, Janick; Geiser, Thomas; Guenat, Olivier Thierry (2014). The potential of microfluidic lung epithelial wounding: towards in vivo-like alveolar microinjuries. Integrative biology : quantitative biosciences from nano to macro, 6(12), pp. 1132-1140. Royal Society of Chemistry 10.1039/c4ib00149d

Ruppen, Janine; Cortes-Dericks, Lourdes; Marconi, Emanuele; Karoubi, Golnaz; Schmid, Ralph; Peng, Renwang; Marti, Thomas; Guenat, Olivier Thierry (2014). A microfluidic platform for chemoresistive testing of multicellular pleural cancer spheroids. Lab on a chip, 14(6), pp. 1198-1205. Royal Society of Chemistry 10.1039/c3lc51093j


Das, Tamal; Meunier, Liliane; Barbe, Laurent; Provencher, Diane; Guenat, Olivier Thierry; Gervais, Thomas; Mes-Masson, Anne-Marie (2013). Empirical chemosensitivity testing in a spheroid model of ovarian cancer using a microfluidics-based multiplex platform. Biomicrofluidics, 7(1), p. 11805. American Institute of Physics 10.1063/1.4774309


Felder, Marcel; Sallin, Pauline; Barbe, Laurent; Haenni, Beat; Gazdhar, Amiq; Geiser, Thomas; Guenat, Olivier (2012). Microfluidic wound-healing assay to assess the regenerative effect of HGF on wounded alveolar epithelium. Lab on a chip, 12(3), pp. 640-6. Cambridge: Royal Society of Chemistry 10.1039/c1lc20879a


Marconi, Emanuele; Schoeni, Anna; Barbe, Laurent; Gazdhar, Amiq; Geiser, Thomas; Guenat, Olivier Thierry (2011). Lung on a chip: Co-culture of alveolar epithelial cells and bone marrow derived stromal stem cells in a microfluidic system. European respiratory journal, 38(Suppl 55), P4585. European Respiratory Society

Felder, Marcel; Sallin, Pauline; Barbe, Laurent; Gazdhar, Amiq; Geiser, Thomas; Guenat, Olivier Thierry (2011). Lung on Chip: In vitro HGF effects on injured alveolar A549 epithelial cells in microfluidic system. European respiratory journal, 38(Suppl 55), P4585. European Respiratory Society


Carrion, L; Hamel, E; Leblanc-Hotte, A; Boudoux, C; Guenat, O; Maciejko, R (2009). Characterization of microfluidic systems with Doppler optical coherence tomography. In: Photonics North 2009. Quebec, Canada. 24-27 May 2009. 10.1117/12.839798


Danelon, Christophe; Terrettaz, Samuel; Guenat, Olivier; Koudelka, Milena; Vogel, Horst (2008). Probing the function of ionotropic and G protein-coupled receptors in surface-confined membranes. Methods, 46(2), pp. 104-15. San Diego, Calif.: Elsevier 10.1016/j.ymeth.2008.07.004

Generelli, Silvia; Jacquemart, Renaud; de Rooij, Nico F; Jolicoeur, Mario; Koudelka-Hep, Milena; Guenat, Olivier T (2008). Potentiometric platform for the quantification of cellular potassium efflux. Lab on a chip, 8(7), pp. 1210-5. Cambridge: Royal Society of Chemistry 10.1039/b801042k


Guenat, Olivier T; Generelli, Silvia; de Rooij, Nicolaas F; Koudelka-Hep, Milena; Berthiaume, François; Yarmush, Martin L (2006). Development of an array of ion-selective microelectrodes aimed for the monitoring of extracellular ionic activities. Analytical chemistry, 78(21), pp. 7453-60. Washington, D.C.: American Chemical Society 10.1021/ac0609733


Berdondini, L; van der Wal, P D; Guenat, O; de Rooij, N F; Koudelka-Hep, M; Seitz, P; Kaufmann, R; Metzler, P; Blanc, N; Rohr, S (2005). High-density electrode array for imaging in vitro electrophysiological activity. Biosensors & bioelectronics, 21(1), pp. 167-74. Barking, UK: Elsevier 10.1016/j.bios.2004.08.011


Guenat, O T; Boulard, G; Dufour, Jean-François; de Rooij, N F; Koudelka-Hep, M (2004). Development of a multifunctional platform for extra- and intracellular ionic activities recording. IEEE Engineering in Medicine and Biology Society conference proceedings, 2004, pp. 2546-2548. Piscataway, N.J.: IEEE Service Center


Guenat, OT; van der Schoot BH, ; Morf, WE; de Rooij NF, (2000). Triangle-programmed coulometric nanotitrations completed by continuous flow with potentiometric detection. Analytical chemistry, 72(7), pp. 1585-90. Washington, D.C.: American Chemical Society 10.1021/ac990488q


Guenat, Olivier; Morf, Werner; Van der Schoot, Bart; de Rooij, Nico (1998). Universal Coulometric Nanotitrators with Potentiometric Detection. Analytica Chimica Acta, 1998(361), pp. 261-272. Amsterdam: Elsevier 10.1016/S0003-2670(98)00034-8

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