Bufalari, A.; Maggio, C.; Cerasoli, I.; Morath, Ute; Adami, Chiara (2012). Preemptive carprofen for peri-operative analgesia in dogs undergoing Tibial Plateau Leveling Osteotomy (TPLO): a prospective, randomized, blinded, placebo controlled clinical trial. Schweizer Archiv für Tierheilkunde, 154(3), pp. 105-11. Bern: Huber 10.1024/0036-7281/a000308
Full text not available from this repository. (Request a copy)Eighteen client-owned dogs undergoing Tibial Plateau Leveling Osteotomy (TPLO) were included in this blinded clinical study and randomly assigned to one of two treatment groups. Group C (carprofen) received intravenous (IV) carprofen, 4 mg/kg, prior to anesthesia, whereas group P (placebo) received IV saline. General anesthesia was maintained with isoflurane in oxygen and a constant rate infusion (CRI) of sufentanyl IV. Intra-operatively, assessment of nociception was based on changes in physiological parameters and on the analgesics requirement, whereas in the post-operative period evaluation of pain was performed by using a Hellyer and Gaynor pain score and by comparing the doses of rescue buprenorphine required by the two treatment groups. Although no statistically significant differences in intra-operative sufentanyl doses were found between treatment groups, group C had superior cardiovascular stability, and lower post-operative pain scores and rescue buprenorphine doses than group P. Our results indicate that administration of carprofen prior to surgery was effective in improving peri-operative analgesia in dogs undergoing TPLO.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > DKV - Anaesthesiology |
UniBE Contributor: |
Morath, Ute, Adami, Chiara |
ISSN: |
0036-7281 |
Publisher: |
Huber |
Language: |
English |
Submitter: |
Andrea Stettler |
Date Deposited: |
15 Nov 2013 12:16 |
Last Modified: |
05 Dec 2022 14:26 |
Publisher DOI: |
10.1024/0036-7281/a000308 |
PubMed ID: |
22378051 |
Additional Information: |
Notes: Bufalari, A |
URI: |
https://boris.unibe.ch/id/eprint/38982 |
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