Emergence of extensively drug-resistant Haemophilus parainfluenzae in Switzerland

Tinguely, Regula; Seiffert, Salome Nadja; Furrer, Hansjakob; Perreten, Vincent; Droz, Sara Christine; Endimiani, Andrea (2013). Emergence of extensively drug-resistant Haemophilus parainfluenzae in Switzerland. Antimicrobial agents and chemotherapy, 57(6), pp. 2867-2869. American Society for Microbiology 10.1128/AAC.00221-13

Full text not available from this repository. (Request a copy)

Two homosexual men were colonized in the urethra with Haemophilus parainfluenzae nonsusceptible to ampicillin (MIC, 8 μg/ml), amoxicillin-clavulanate (MIC, 4 μg/ml), cefotaxime (MIC, 1.5 μg/ml), cefepime (MIC, 3 μg/ml), meropenem (MIC, 0.5 μg/ml), cefuroxime, azithromycin, ciprofloxacin, tetracycline, and chloramphenicol (all MICs, ≥ 32 μg/ml). Repetitive extragenic palindromic PCR (rep-PCR) showed that the strains were indistinguishable. The isolates had amino acid substitutions in PBP3, L4, GyrA, and ParC and possessed Mef(A), Tet(M), and CatS resistance mechanisms. This is the first report of extensively drug-resistant (XDR) H. parainfluenzae.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Research Foci > Host-Pathogen Interaction
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology
04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP)
05 Veterinary Medicine > Department of Infectious Diseases and Pathobiology (DIP) > Institute of Veterinary Bacteriology

UniBE Contributor:

Seiffert, Salome Nadja; Furrer, Hansjakob; Perreten, Vincent; Droz, Sara Christine and Endimiani, Andrea

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health
600 Technology > 630 Agriculture

ISSN:

0066-4804

Publisher:

American Society for Microbiology

Language:

English

Submitter:

Susanne Portner

Date Deposited:

21 Mar 2014 11:42

Last Modified:

11 Feb 2015 14:22

Publisher DOI:

10.1128/AAC.00221-13

PubMed ID:

23545526

URI:

https://boris.unibe.ch/id/eprint/43837

Actions (login required)

Edit item Edit item
Provide Feedback