Anaesthesia with medetomidine-ketamine-isoflurane with and without midazolam, in eight captive Chimpanzees (Pan troglodytes) premedicated with oral zuclopenthixol

Adami, Chiara; Wenker, C.; Hoby, S.; Morath, Ute; Bergadano, A. (2013). Anaesthesia with medetomidine-ketamine-isoflurane with and without midazolam, in eight captive Chimpanzees (Pan troglodytes) premedicated with oral zuclopenthixol. Schweizer Archiv für Tierheilkunde, 155(8), pp. 471-476. Huber 10.1024/0036-7281/a000493

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In 8 captive adult chimpanzees of various ages premedicated with oral zuclopenthixol anaesthesia was induced intramuscularly with a combination of medetomidine and ketamine (40 or 50 µg/kg and 5 mg/kg, IM, respectively), with and without midazolam (0.05 mg/kg), and maintained with isoflurane in oxygen. At the end of the procedure, sedation was reversed with atipamezole (0.25 mg/kg, IM) and sarmazenil (0.005 mg/kg, IM) when midazolam had been administered. Oral zuclopenthixol resulted in tranquillization of the whole group and only one animal required a second dart injection to achieve adequately deep anaesthesia. Effective and reliable anaesthesia was achieved in all apes; the depth of hypnosis was stable and sudden arousal did not occur. Physiological parameters remained within normal ranges in the majority of the animals; however, manageable anaesthesia-related complications, namely apnoea after darting, hypotension, hypoventilation, hypoxemia and prolonged recovery, occurred in 6 out of 8 animals. The use of monitoring devices was essential to guarantee adequate management of these complications.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > DKV - Anaesthesiology

UniBE Contributor:

Adami, Chiara and Morath, Ute

Subjects:

600 Technology > 630 Agriculture

ISSN:

0036-7281

Publisher:

Huber

Language:

German

Submitter:

Susanne Portner

Date Deposited:

28 Jul 2014 16:22

Last Modified:

23 Apr 2015 13:19

Publisher DOI:

10.1024/0036-7281/a000493

PubMed ID:

23919974

Uncontrolled Keywords:

chimpanzee, ketamine, medetomidine, midazolam, Pan troglodytes, zuclopenthixol

URI:

https://boris.unibe.ch/id/eprint/44707

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