Interferons not only exert a fundamental role during inflammation and immune responses but also modulate the activity of hematopoietic stem cells during homeostatic and demand-adapted hematopoiesis. Identical mechanisms regulate the homeostasis and proliferation of leukemic stem cells (LSCs). Understanding these mechanisms may lead to novel therapeutic approaches against leukemia.
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Item Type: |
Journal Article
(Further Contribution)
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Division/Institute: |
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Tumor-Immunologie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Tumor-Immunologie
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Medical Oncology |
UniBE Contributor: |
Schürch, Christian, Riether, Carsten, Ochsenbein, Adrian |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
2162-4011 |
Publisher: |
Landes Bioscience |
Language: |
English |
Submitter: |
Marianne Zahn
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Date Deposited: |
12 May 2014 11:05 |
Last Modified: |
05 Dec 2022 14:30 |
Publisher DOI: |
10.4161/onci.24572 |
PubMed ID: |
23894719 |
Uncontrolled Keywords: |
hematopoiesis, hematopoietic stem cells, interferon, leukemia, leukemia stem cells |
BORIS DOI: |
10.7892/boris.45041 |
URI: |
https://boris.unibe.ch/id/eprint/45041 |
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