Nanomaterials and the human lung: what is known and what must be deciphered to realise their potential advantages?

Jud, Corinne; Clift, Martin; Petri-Fink, Alke; Rothen-Rutishauser, Barbara (2013). Nanomaterials and the human lung: what is known and what must be deciphered to realise their potential advantages? Swiss medical weekly, 143, w13758. EMH Schweizerischer Ärzteverlag 10.4414/smw.2013.13758

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Due to the constant expansion within the nanotechnology industry in the last decade, nanomaterials are omnipresent in society today. Nanotechnology-based products have numerous different applications ranging from electronic (e.g., advanced memory chips) to industrial (e.g., coatings or composites) to biomedical (e.g., drug delivery systems, diagnostics). Although these new nanomaterials can be found in many "everyday" products, their effects on the human body have still to be investigated in order to identify not only their risk, but also their potential benefits towards human health. Since the lung is commonly thought to be the main portal of entry into the human body for nanomaterials released within the environment, this review will attempt to summarise the current knowledge and understanding of how nanomaterials interact with the respiratory tract. Furthermore, the advantages and disadvantages of different experimental model systems that are commonly used to study this exposure route to the human body will be discussed.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Mu50 > Forschungsgruppe Pneumologie (Erwachsene)
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Pneumology

UniBE Contributor:

Clift, Martin and Rothen-Rutishauser, Barbara

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1424-7860

Publisher:

EMH Schweizerischer Ärzteverlag

Language:

English

Submitter:

Rahel Holderegger

Date Deposited:

30 Apr 2014 10:36

Last Modified:

03 Jan 2015 21:26

Publisher DOI:

10.4414/smw.2013.13758

PubMed ID:

23519981

BORIS DOI:

10.7892/boris.48229

URI:

https://boris.unibe.ch/id/eprint/48229

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