Rothen-Rutishauser, Barbara

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2014

Fytianos, Kleanthis; Rodriguez-Lorenzo, Laura; Clift, Martin J D; Blank, Fabian; Vanhecke, Dimitri; Von Garnier, Christophe; Petri-Fink, Alke; Rothen-Rutishauser, Barbara (2014). Uptake efficiency of surface modified gold nanoparticles does not correlate with functional changes and cytokine secretion in human dendritic cells in vitro. Nanomedicine : nanotechnology, biology, and medicine, 11(3), pp. 633-644. Elsevier 10.1016/j.nano.2014.11.004

Beyeler, Seraina Martina; Chortarea, Savvina; Rothen-Rutishauser, Barbara; Petri-Fink, Alke; Tschanz, Stefan A.; Von Garnier, Christophe; Blank, Fabian (10 November 2014). Effects of multi-walled carbon nanotubes in chronic obstructive pulmonary disease: An optimized human in vitro airway epithelial model for fibre exposure at the air-liquid interface (Unpublished). In: Annual Meeting of the Swiss Aerosol Group. Bern. 10.11.2014.

Beyeler, Seraina Martina; Chortarea, Savvina; Rothen-Rutishauser, Barbara; Petri-Fink, Alke; Tschanz, Stefan A.; Von Garnier, Christophe; Blank, Fabian (5 November 2014). A human in vitro airway epithelial model to study health effects of multi-walled carbon nanotubes (MWCNT) (Unpublished). In: Day of Clinical Research. Bern. 05.11.2014.

Seydoux, Emilie; Rodriguez-Lorenzo, Laura; Fytianos, Kleanthis; Petri-Fink, Alke; Rothen-Rutishauser, Barbara; Von Garnier, Christophe; Blank, Fabian (5 November 2014). Amine-functionalized PVA-coated Gold nanoparticles enhance specific CD4+ T-cell proliferation in vivo (Unpublished). In: Day of Clinical Research. Bern. 05.11.2014.

Beyeler, Seraina Martina; Chortarea, Savvina; Rothen-Rutishauser, Barbara; Petri-Fink, Alke; Tschanz, Stefan A.; Von Garnier, Christophe; Blank, Fabian (9 May 2014). A human in vitro airway wall model to study effects of multi-walled carbon nanotubes on cells from healthy subjects and subjects suffering from COPD (Unpublished). In: Annual Meeting of the Swiss Society for Pneumology. Interlaken. 09.05.2014.

Seydoux, Emilie; Rodriguez-Lorenzo, Laura; Fytianos, Kleanthis; Petri-Fink, Alke; Rothen-Rutishauser, Barbara; Von Garnier, Christophe; Blank, Fabian (9 May 2014). Nanoparticles decrease antigen-processing in dendritic cells without affecting other cell functions (Unpublished). In: Annual Meeting of the Swiss Society for Pneumology. Interlaken. 09.05.2014.

Rodriguez-Lorenzo, Laura; Fytianos, Kleanthis; Blank, Fabian; Von Garnier, Christophe; Rothen-Rutishauser, Barbara; Petri-Fink, Alke (2014). Fluorescence-encoded gold nanoparticles: library design and modulation of cellular uptake into dendritic cells. Small, 10(7), pp. 1341-1350. Wiley-VCH 10.1002/smll.201302889

Schild, Christof; Hahn, Dagmar Karen; Schaller, André; Jackson, Christopher; Rothen-Rutishauser, Barbara; Mirkovitch, Jelena; Nuoffer, Jean-Marc (2014). Mitochondrial leucine tRNA level and PTCD1 are regulated in response to leucine starvation. Amino acids, 46(7), pp. 1775-1783. Springer 10.1007/s00726-014-1730-2

Seydoux, Emilie; Rodriguez-Lorenzo, Laura; Fytianos, Kleanthis; Petri-Fink, Alke; Rothen-Rutishauser, Barbara; Von Garnier, Christophe; Blank, Fabian (March 2014). Particulate size modulates antigen processing in dendritic cells (Unpublished). In: World Immune Regulation Meeting (WIRM). Davos, Switzerland. 19.-22.03.2014.

Rothen-Rutishauser, Barbara; Kuhn, Dagmar; Ali, Zulqurnain; Gasser, Michael; Amin, Faheem; Parak, Wolfang J.; Vanhecke, Dimitri; Fink, Alke; Gehr, Peter; Brandenberger, Stefanie Christina (2014). Quantification of gold nanoparticle cell uptake under controlled biological conditions and adequate resolution. Nanomedicine, 9(5), pp. 607-621. Future Medicine 10.2217/nnm.13.24

Clift, Martin; Endes, Carola; Vanhecke, Dimitri; Wick, Peter; Gehr, Peter; Schins, Roel P. F.; Petri-Fink, Alke; Rothen-Rutishauser, Barbara (2014). A comparative study of different in vitro lung cell culture systems to assess the most beneficial tool for screening the potential adverse effects of carbon nanotubes. Toxicological sciences, 137(1), pp. 55-64. Oxford University Press 10.1093/toxsci/kft216

Seydoux, Emilie; Rothen-Rutishauser, Barbara; Nita, Izabela Magdalena; Balog, S; Gazdhar, Amiq Ur Rahman; Stumbles, PA; Petri-Fink, Alke; Blank, Fabian; Von Garnier, Christophe (2014). Size-dependent accumulation of particles in lysosomes modulates dendritic cell function through impaired antigen degradation. International journal of nanomedicine, 9, pp. 3885-3902. DOVE Medical Press 10.2147/IJN.S64353

Kuhn, Dagmar A; Vanhecke, Dimitri; Michen, Benjamin; Blank, Fabian; Gehr, Peter; Petri-Fink, Alke; Rothen-Rutishauser, Barbara (2014). Different endocytotic uptake mechanisms for nanoparticles in epithelial cells and macrophages. Beilstein journal of nanotechnology, 5, pp. 1625-1636. Beilstein-Institut zur Förderung der Chemischen Wissenschaften 10.3762/bjnano.5.174

Vanhecke, Dimitri; Rodriguez-Lorenzo, Laura; Clift, Martin J D; Blank, Fabian; Petri-Fink, Alke; Rothen-Rutishauser, Barbara (2014). Quantification of nanoparticles at the single-cell level: an overview about state-of-the-art techniques and their limitations. Nanomedicine, 9(12), pp. 1885-1900. Future Medicine 10.2217/nnm.14.108

2013

Steiner, Sandro; Czerwinski, Jan; Compte, Pierre; Popovicheva, Olga; Kireeva, Elena; Müller, Loretta; Heeb, Norbert; Mayer, Andreas; Fink, Alke; Rothen-Rutishauser, Barbara (2013). Comparison of the toxicity of diesel exhaust produced by bio- and fossil diesel combustion in human lung cells in vitro. Atmospheric environment, 81, pp. 380-388. Pergamon 10.1016/j.atmosenv.2013.08.059

Behra, Renata; Sigg, Laura; Clift, Martin; Herzog, Fabian; Minghetti, Matteo; Johnston, Blair; Petri-Fink, Alke; Rothen-Rutishauser, Barbara (2013). Bioavailability of silver nanoparticles and ions: from a chemical and biochemical perspective. Journal of the Royal Society Interface, 10(87), p. 20130396. The Royal Society 10.1098/rsif.2013.0396

Blank, Fabian; Stumbles, P; Strickland, D; Rothen-Rutishauser, Barbara; Holt, P; Seydoux, Emilie; von Garnier, Christophe (August 2013). Delivery of nanocarriers for pulmonary vaccination: Recent advances and challenges (Unpublished). In: Microscopy Conference. Regensburg. 25.-30.8.2013.

Blank, Fabian; Stumbles, Philip A.; Seydoux, Emilie; Holt, Patrick G.; Fink, Alke; Rothen-Rutishauser, Barbara; Strickland, Deborah H.; Von Garnier, Christophe (2013). Size-Dependent Uptake of Particles by Pulmonary Antigen-Presenting Cell Populations and Trafficking to Regional Lymph Nodes. American journal of respiratory cell and molecular biology, 49(1), pp. 67-77. American Lung Association 10.1165/rcmb.2012-0387OC

Von Garnier, Christophe; Rothen-Rutishauser, Barbara; Blank, Fabian (2013). Nanoparticles in the respiratory tract: Modulation of Antigen-presenting cell function. Journal of Environmental Immunology and Toxicology, 1(3), pp. 140-149. STM Connect

Hirsch, Vera; Kinnear, Calum; Moniatte, Marc; Rothen-Rutishauser, Barbara; Clift, Martin; Fink, Alke (2013). Surface charge of polymer coated SPIONs influences the serum protein adsorption, colloidal stability and subsequent cell interaction in vitro. Nanoscale, 5(9), pp. 3723-3732. Royal Society of Chemistry 10.1039/c2nr33134a

Herzog, Fabian; Clift, Martin; Piccapietra, Flavio; Behra, Renata; Schmid, Otmar; Petri-Fink, Alke; Rothen-Rutishauser, Barbara (2013). Exposure of silver-nanoparticles and silver-ions to lung cells in vitro at the air-liquid interface. Particle and fibre toxicology, 10(1), p. 11. BioMed Central 10.1186/1743-8977-10-11

Blank, Fabian; Stumbles, P; Strickland, D; Rothen-Rutishauser, Barbara; Holt, P; Seydoux, Emilie; von Garnier, Christophe (April 2013). Delivery of antigens for vaccination: Recent advances and challenges (Unpublished). In: International Society for Aerosols in Medicine Conference. Chapel Hill, North Carolina. 6.-10.4.2013.

Jud, Corinne; Clift, Martin; Petri-Fink, Alke; Rothen-Rutishauser, Barbara (2013). Nanomaterials and the human lung: what is known and what must be deciphered to realise their potential advantages? Swiss medical weekly, 143, w13758. EMH Schweizerischer Ärzteverlag 10.4414/smw.2013.13758

2012

Schleh, Carsten; Rothen-Rutishauser, Barbara M.; Blank, Fabian; Lauenstein, Hans D.; Nassimi, Matthias; Krug, Norbert; Braun, Armin; Erpenbeck, Veit J.; Gehr, Peter; Hohlfeld, Jens M. (2012). Surfactant protein D modulates allergen particle uptake and inflammatory response in a human epithelial airway model. Respiratory research, 13(8), p. 8. London: BioMed Central 10.1186/1465-9921-13-8

Gasser, Michael; Wick, Peter; Clift, Martin JD; Blank, Fabian; Diener, Liliane; Yan, Bing; Gehr, Peter; Krug, Harald F.; Rothen-Rutishauser, Barbara (2012). Pulmonary surfactant coating of multi-walled carbon nanotubes (MWCNTs) influences their oxidative and pro-inflammatory potential in vitro. Particle and fibre toxicology, 9(1), p. 17. London: BioMed Central 10.1186/1743-8977-9-17

von Garnier, C; Rothen-Rutishauser, B; Fink, A (2012). A particular therapy. International Innovation.

Mahmoudi, M; Hofmann, H; Rothen-Rutishauser, B; Petri-Fink, A (2012). Assessing the in vitro and in vivo toxicity of superparamagnetic iron oxide nanoparticles. Chemical reviews, 112((4)), pp. 2323-38. Washington, D.C.: American Chemical Society 10.1021/cr2002596

Müller, I; Comte P, J; Czerwinski, J; Kasper, M; Meyer, ACR; Schmid, A; Rosinus, I; Clift, MJD; Steiner, S; Gehr, P; Rothen-Rutishauser, B (2012). Investigating the potential for different scooter and car exhaust emissions to cause cytotoxic and (pro-)inflammatory responses to a 3D in vitro model of the human epithelial airway. Toxicological and environmental chemistry, 94((1)), pp. 164-180. Abingdon, UK: Taylor & Francis

Mahmoudi, M; Saeedi-Eslami, SN; Shokrgozar, MA; Azadmanesh, K; Hasanloo, M; Kalhor, H; Burtea, C; Rothen-Rutishauser, B; Laurent, S; Sheibani, S; Vali, H (2012). Cell "Vision": Complementary factor of protein corona in nano toxicology. Nanoscale, 4((17)), pp. 5461-8. Cambridge: Royal Society of Chemistry 10.1039/c2nr31185b

Steiner, S; Muller, I; Popovicheva, OB; Raemy, DO; Czerwinski, J; Comte, P; Mayer, A; Gehr, P; Rothen-Rutishauser, B; Clift, MJD (2012). Cerium dioxide nanoparticles can interfere with the associated cellular mechanistic response to diesel exhaust exposure. Toxicology letters, 214((2)), pp. 218-25. Amsterdam: Elsevier 10.1016/j.toxlet.2012.08.026

Raemy, David O.; Grass, Robert N.; Stark, Wendelin J.; Schumacher, Christoph M.; Clift, Martin JD; Gehr, Peter; Rothen-Rutishauser, Barbara (2012). Effects of flame made zinc oxide particles in human lung cells - a comparison of aerosol and suspension exposures. Particle and fibre toxicology, 9(1), p. 33. London: BioMed Central 10.1186/1743-8977-9-33

Clift, MJ; Raemy, DO; Endes, C; Ali, Z; Lehmann, AD; Brandenberger, C; Petri-Fink, A; Wick, P; Parak, WJ; Gehr, P; Schins, RP; Rothen-Rutishauser, B (2012). Can the Ames test provide an insight into nano-object mutagenicity? Investigating the interaction between nano-objects and bacteria. Nanotoxicology London: Informa Healthcare

Rivera-Gil, P; Clift, MJ; Rothen-Rutishauser, B; Parak, WJ (2012). Methods for understanding the interaction between nanoparticles and cells. Methods in molecular biology(926), pp. 22-56. Totowa, N.J.: Humana Press

Könczöl, M; Goldenberg, E; Ebeling, S; Schäfer, B; Garcia-Käufer, M; Gminski, R; Grobéty, B; Rothen-Rutishauser, B; Merfort, I; Gieré, R; Mersch-Sundermann, V (2012). Cellular uptake and toxic effects of fine and ultrafine metal-sulfate particles in human A549 lung epithelial cells. Chemical research in toxicology, 25((12)), pp. 2687-703. Washington, D.C.: American Chemical Society 10.1021/tx300333z

Petri-Fink, A; Rothen-Rutishauser, B (2012). Nanoparticles and cells: an interdisciplinary approach. CHIMIA, 66((3)), pp. 104-9. Bern: Schweizerische Chemische Gesellschaft 10.2533/chimia.2012.104

Jud, C; Angeloni, L; Muller, M; Liley, A; Petri-Fink, B; Rothen-Rutishauser, B (2012). The lung in a dish - a new tool to study the interaction of inhaled (nano) material with lung cells. In: Annual meeting European Respiratory Society. A - Vienna: Annual meeting European Respiratory Society

Rothen-Rutishauser, B; Clift, MJD; Jud, C; Fink, A; Wick, P (2012). Human epithelial cells in vitro - are they an advantageous tool to help understand the nanomaterial biological barrier interaction? EURO-NanoTox-Letters, 4((1)), pp. 1-20. Graz: BioNanoNet Forschungsgesellschaft

2011

Raemy, David O; Limbach, Ludwig K; Rothen-Rutishauser, Barbara; Grass, Robert N; Gehr, Peter; Birbaum, Karin; Brandenberger, Christina; Günther, Detlef; Stark, Wendelin J (2011). Cerium oxide nanoparticle uptake kinetics from the gas-phase into lung cells in vitro is transport limited. European journal of pharmaceutics and biopharmaceutics, 77(3), pp. 368-75. Amsterdam: Elsevier 10.1016/j.ejpb.2010.11.017

Clift, Martin J D; Gehr, Peter; Rothen-Rutishauser, Barbara (2011). Nanotoxicology: a perspective and discussion of whether or not in vitro testing is a valid alternative. Archives of toxicology, 85(7), pp. 723-31. Berlin: Springer-Verlag 10.1007/s00204-010-0560-6

Schleh, Carsten; Rothen-Rutishauser, Barbara; Kreyling, Wolfgang G (2011). The influence of pulmonary surfactant on nanoparticulate drug delivery systems. European journal of pharmaceutics and biopharmaceutics, 77(3), pp. 350-2. Amsterdam: Elsevier 10.1016/j.ejpb.2010.12.025

Thurnherr, Tina; Brandenberger, Christina; Fischer, Kathrin; Diener, Liliane; Manser, Pius; Maeder-Althaus, Xenia; Kaiser, Jean-Pierre; Krug, Harald F; Rothen-Rutishauser, Barbara; Wick, Peter (2011). A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro. Toxicology letters, 200(3), pp. 176-86. Amsterdam: Elsevier 10.1016/j.toxlet.2010.11.012

Lehmann, Andrea D; Daum, Nicole; Bur, Michael; Lehr, Claus-Michael; Gehr, Peter; Rothen-Rutishauser, Barbara M (2011). An in vitro triple cell co-culture model with primary cells mimicking the human alveolar epithelial barrier. European journal of pharmaceutics and biopharmaceutics, 77(3), pp. 398-406. Amsterdam: Elsevier 10.1016/j.ejpb.2010.10.014

Blank, Fabian; Wehrli, Marc; Lehmann, Andrea; Baum, Oliver; Gehr, Peter; von Garnier, Christophe; Rothen-Rutishauser, Barbara M (2011). Macrophages and dendritic cells express tight junction proteins and exchange particles in an in vitro model of the human airway wall. Immunobiology, 216(1-2), pp. 86-95. Amsterdam: Elsevier 10.1016/j.imbio.2010.02.006

Clift, Martin J D; Foster, E Johan; Vanhecke, Dimitri; Studer, Daniel; Wick, Peter; Gehr, Peter; Rothen-Rutishauser, Barbara; Weder, Christoph (2011). Investigating the interaction of cellulose nanofibers derived from cotton with a sophisticated 3D human lung cell coculture. Biomacromolecules, 12(10), pp. 3666-73. Washington, D.C.: American Chemical Society 10.1021/bm200865j

Mühlfeld, Christian; Poland, Craig A; Duffin, Rodger; Brandenberger, Christina; Murphy, Fiona A; Rothen-Rutishauser, Barbara; Gehr, Peter; Donaldson, Ken (2011). Differential effects of long and short carbon nanotubes on the gas-exchange region of the mouse lung. Nanotoxicology, 6, pp. 867-879. London: Informa Healthcare 10.3109/17435390.2011.626533

Strickland, DH; Blank, F; Wikstrom, M; Smith, M; Thomas, JA; Rothen-Rutishauser, B; Holt, P; Stumbles, Ph; von Garnier, C (2011). Resident common precursors for dendritic cells and macrophages in the lung parenchyma. In: Jahreskongress American Thoracic Society. Jahreskongress American Thoracic Society

Blank, F; Gerber, P; Rothen-Rutishauser, B; Sakulkhu, U; Salaklang, J; de Peyer, K; Gehr, P; Nicod, LP; Hofmann, H; Geiser, T; Petri-Fink, A; von Garnier, C (2011). Biomedical nanoparticles retain an immature like functional state and show reduced antigen specific CD4+ T cell stimulation in vitro. Nanotoxicology(Jan 2011) London: Informa Healthcare

Ahmad, S; Raemy, DO; Loader, JE; Kailey, JM; Neeves, KB; White, CW; Ahmad, A; Gehr, P; Rothen-Rutishauser, B (2011). Interaction and localization of synthetic nanoparticles in healthy and cystic fibrosis airway epithelial cells: Effect of ozone exposure. Journal of aerosol medicine and pulmonary drug delivery, 25(1), pp. 7-15. New York, N.Y.: Mary Ann Liebert 10.1089/jamp.2011.0889

Könczöl, M; Ebeling, S; Goldenberg, E; Treude, F; Gminski, R; Gieré, R; Grobéty, B; Rothen-Rutishauser, B; Merfort, I; Mersch-Sundermann, V (2011). Cytotoxicity and genotoxicity of size-fractionated iron oxide (magnetite) in A549 human lung epithelial cells: role of ROS, JNK and NF-KB. Chemical research in toxicology, 24(9), pp. 1460-75. Washington, D.C.: American Chemical Society 10.1021/tx200051s

Frick, R; Müller-Edenhorn, B; Schlicker, A; Rothen-Rutishauser, B; Raemy, DO; Günther, D; Hattendorf, B; Stark, W; Beck-Schimmer, B (2011). Comparison of manganese oxide nanoparticles and manganese sulfate with regard to oxidative stress, uptake and apoptosis in alveolar epithelial cells. Toxicology letters, 205(2), pp. 163-72. Amsterdam: Elsevier 10.1016/j.toxlet.2011.05.1037

Wick, P; Clift, MJ; Rösslein, M; Rothen-Rutishauser, B (2011). A brief summary of carbon nanotubes science and technology: a health and safety perspective. ChemSusChem, 4(7), pp. 905-11. Weinheim: Wiley-VCH 10.1002/cssc.201100161

Paur, HR; Cassee, FR; Teeguarden, J; Fissan, H; Diabate, S; Aufderheide, M; Kreyling, WG; Hanninen, O; Kasper, G; Riediker, M; Rothen-Rutishauser, B; Schmid, O (2011). In-vitro cell exposure studies for the assessment of nanoparticle toxicity in the lung - A dialog between aerosol science and biology. Journal of aerosol science, 42(10), pp. 668-692. Amsterdam: Elsevier 10.1016/j.jaerosci.2011.06.005

Rothen-Rutishauser, B; Blank, F; Petri-Fink, A; Clift, MJ; Geiser, T; von Garnier, C (2011). Laser scanning microscopy combined with image restoration to analyse and quantify the intracellular localisation of fluorescently labelled nanoparticles. Imaging & microscopy Weinheim: GIT-Verlag

Rothen-Rutishauser, B (2011). Investigating nanoparticle mutagenicity: Can nanoparticle-bacterial interactions provide an insight into the unknown? In: 15th ETH-Conference on Cumbustion Generated Nanoparticles. Zürich: 15th ETH-Conference on Cumbustion Generated Nanoparticles

Rothen-Rutishauser, B (2011). Co-cultures of immune and lung cells for in vitro assessment of nanoparticle toxicity. In: FP-7-Nanomune closing workshop: Nano-immuno-interactions. Stockholm.

Rothen-Rutishauser, B (2011). Nanotechnologie - Nutzen und Risiken. In: Kollegium Spiritus Sanctus, organised by the Fachschaft Chemie - Biologie. Brig.

Rothen-Rutishauser, B (2011). Nanopartikel-Lungenzell-Interaktionen: Risiken und Chancen. In: Jahrestagung Silag, Zürcherische Arbeitsgemeinschaft zur Erforschung und Bekämpfung der Staublungen in der Schweiz, Adophe Merckle Institute. Marly.

Rothen-Rutishauser, B (2011). Risk assessment of nanomaterials - Do we need to worry? In: Seminars in molecular toxicology, Molecular and Systems Toxicology, Department of Pharmaceutical Sciences, University of Basel. Basel.

Rothen-Rutishauser, B (2011). Air-liquid exposures of particles onto lung culture surfaces: A new standard to study particle-cell interactions. In: 18th Congress of International Society for Aerosols in Medicine. Rotterdam.

2010

Brandenberger, Christina; Rothen-Rutishauser, Barbara; Mühlfeld, Christian; Schmid, Otmar; Ferron, George A; Maier, Konrad Ludwig; Gehr, Peter; Lenz, Anke Gabriele (2010). Effects and uptake of gold nanoparticles deposited at the air–liquid interface of a human epithelial airway model. Toxicology and Applied Pharmacology, 242(1), pp. 56-65. Amsterdam: Elsevier 10.1016/j.taap.2009.09.014

Müller, Loretta Lina; Riediker, Michael; Wick, Peter; Mohr, Martin; Gehr, Peter; Rothen-Rutishauser, Barbara (2010). Oxidative stress and inflammation response after nanoparticle exposure: differences between human lung cell monocultures and an advanced three-dimensional model of the human epithelial airways. Journal of The Royal Society Interface, 7(Suppl_1), S27-S40. London: The Royal Society 10.1098/rsif.2009.0161.focus

Brandenberger, Christina; Clift, Martin J D; Vanhecke, Dimitri; Mühlfeld, Christian; Stone, Vicki; Gehr, Peter; Rothen-Rutishauser, Barbara (2010). Intracellular imaging of nanoparticles: is it an elemental mistake to believe what you see? Particle and fibre toxicology, 7(1), p. 15. London: BioMed Central 10.1186/1743-8977-7-15

Rothen-Rutishauser, Barbara; Lehmann, Andrea D; Clift, Martin J D; Blank, Fabian; Gehr, Peter (2010). Laser scanning microscopy combined with image restoration to analyse a 3D model of the human epithelial airway barrier. Swiss medical weekly, 140, w13060. Muttenz: EMH Schweizerischer Ärzteverlag 10.4414/smw.2010.13060

Rothen-Rutishauser, Barbara; Brown, David M; Piallier-Boyles, Matthew; Kinloch, Ian A; Windle, Alan H; Gehr, Peter; Stone, Vicki (2010). Relating the physicochemical characteristics and dispersion of multiwalled carbon nanotubes in different suspension media to their oxidative reactivity in vitro and inflammation in vivo. Nanotoxicology, 4(3), pp. 331-42. London: Informa Healthcare 10.3109/17435390.2010.489161

Maina, J N; West, J B; Orgeig, S; Foot, N J; Daniels, C B; Kiama, S G; Gehr, P; Mühlfeld, C; Blank, F; Müller, L; Lehmann, A; Brandenberger, C; Rothen-Rutishauser, B (2010). Recent advances into understanding some aspects of the structure and function of mammalian and avian lungs. Physiological and biochemical zoology, 83(5), pp. 792-807. Chicago, Ill.: University of Chicago Press 10.1086/652244

Brandenberger, Christina; Mühlfeld, Christian; Ali, Zulqurnain; Lenz, Anke-Gabriele; Schmid, Otmar; Parak, Wolfgang J; Gehr, Peter; Rothen-Rutishauser, Barbara (2010). Quantitative evaluation of cellular uptake and trafficking of plain and polyethylene glycol-coated gold nanoparticles. Small, 6(15), pp. 1669-78. Weinheim: Wiley-VCH 10.1002/smll.201000528

Berntsen, P; Park, C Y; Rothen-Rutishauser, B; Tsuda, A; Sager, T M; Molina, R M; Donaghey, T C; Alencar, A M; Kasahara, D I; Ericsson, T; Millet, E J; Swenson, J; Tschumperlin, D J; Butler, J P; Brain, J D; Fredberg, J J; Gehr, P; Zhou, E H (2010). Biomechanical effects of environmental and engineered particles on human airway smooth muscle cells. Interface - journal of the Royal Society, 7 Suppl 3(Suppl 3), S331-S340. London: The Royal Society 10.1098/rsif.2010.0068.focus

Müller, Loretta; Comte, Pierre; Czerwinski, Jan; Kasper, Markus; Mayer, Andreas C R; Gehr, Peter; Burtscher, Heinz; Morin, Jean-Paul; Konstandopoulos, Athanasios; Rothen-Rutishauser, Barbara (2010). New exposure system to evaluate the toxicity of (scooter) exhaust emissions in lung cells in vitro. Environmental science & technology, 44(7), pp. 2632-8. Washington, D.C.: ACS Publications 10.1021/es903146g

Lehmann, Andrea D; Parak, Wolfgang J; Zhang, Feng; Ali, Zulqurnain; Röcker, Carlheinz; Nienhaus, G Ulrich; Gehr, Peter; Rothen-Rutishauser, Barbara (2010). Fluorescent-magnetic hybrid nanoparticles induce a dose-dependent increase in proinflammatory response in lung cells in vitro correlated with intracellular localization. Small, 6(6), pp. 753-62. Weinheim: Wiley-VCH 10.1002/smll.200901770

Lehmann, Andrea; Brandenberger, Christina; Blank, Fabian; Gehr, Peter; Rothen-Rutishauser, Barbara (2010). A 3D model of the human epithelial airway barrier. In: Maguire, Tim; Novik, Eric (eds.) Methods in bioengineering: Alternative technologies to animal testing (pp. 239-260). Artech House

2009

Bur, Michael; Rothen-Rutishauser, Barbara; Huwer, Hanno; Lehr, Claus-Michael (2009). A novel cell compatible impingement system to study in vitro drug absorption from dry powder aerosol formulations. European journal of pharmaceutics and biopharmaceutics, 72(2), pp. 350-7. Amsterdam: Elsevier 10.1016/j.ejpb.2008.07.019

Spahni, Andrea I; Schawalder, Peter; Rothen-Rutishauser, Barbara; Bosshardt, Dieter D; Lang, Niklaus; Stoffel, Michael Hubert (2009). Immunohistochemical localization of RANK, RANKL and OPG in healthy and arthritic canine elbow joints. Veterinary surgery, 38(6), pp. 780-786. Oxford: Wiley-Blackwell 10.1111/j.1532-950X.2009.00566.x

Lehmann, Andrea D; Blank, Fabian; Baum, Oliver; Gehr, Peter; Rothen-Rutishauser, Barbara M (2009). Diesel exhaust particles modulate the tight junction protein occludin in lung cells in vitro. Particle and fibre toxicology, 6, p. 26. London: BioMed Central 10.1186/1743-8977-6-26

Lenz, Anke Gabriele; Karg, Erwin; Lentner, Bernd; Dittrich, Vlad; Brandenberger, Christina; Rothen-Rutishauser, Barbara; Schulz, Holger; Ferron, George A; Schmid, Otmar (2009). A dose-controlled system for air-liquid interface cell exposure and application to zinc oxide nanoparticles. Particle and fibre toxicology, 6, p. 32. London: BioMed Central 10.1186/1743-8977-6-32

Rothen-Rutishauser, Barbara; Grass, Robert N; Blank, Fabian; Limbach, Ludwig K; Mühlfeld, Christian; Brandenberger, Christina; Raemy, David O; Gehr, Peter; Stark, Wendelin J (2009). Direct combination of nanoparticle fabrication and exposure to lung cell cultures in a closed setup as a method to simulate accidental nanoparticle exposure of humans. Environmental science & technology, 43(7), pp. 2634-40. Washington, D.C.: ACS Publications 10.1021/es8029347

Gasser, Michael; Riediker, Michael; Mueller, Loretta; Perrenoud, Alain; Blank, Fabian; Gehr, Peter; Rothen-Rutishauser, Barbara (2009). Toxic effects of brake wear particles on epithelial lung cells in vitro. Particle and fibre toxicology, 6, p. 30. London: BioMed Central 10.1186/1743-8977-6-30

Obregon, Carolina; Rothen-Rutishauser, Barbara; Gerber, Peter; Gehr, Peter; Nicod, Laurent P (2009). Active uptake of dendritic cell-derived exovesicles by epithelial cells induces the release of inflammatory mediators through a TNF-alpha-mediated pathway. American journal of pathology, 175(2), pp. 696-705. New York, N.Y.: Elsevier 10.2353/ajpath.2009.080716

Hofer, Ursula; Lehmann, Andrea D; Waelti, Ernst; Amacker, Mario; Gehr, Peter; Rothen-Rutishauser, Barbara (2009). Virosomes can enter cells by non-phagocytic mechanisms. Journal of liposome research, 19(4), pp. 301-309. New York, N.Y.: Marcel Dekker 10.3109/08982100902911612

Rothen-Rutishauser, B; Blank, F; Mühlfeld, Ch; Gehr, P (2009). Nanoparticle-cell membrane interactions. In: Gehr P, Mühlfeld Ch (ed.) Particle-lung interactions, Second Edition (pp. 226-242). Informa Healthcare

Brandenberger, C; Rothen-Rutishauser, B; Blank, F; Gehr, P; Mühlfeld, C (2009). Particles induce apical plasma membrane enlargement in epithelial lung cell line depending on particle surface area dose. Respiratory research, 10(1), p. 22. London: BioMed Central 10.1186/1465-9921-10-22

Blank, Fabian; Gehr, Peter; Rothen-Rutishauser, Barbara (2009). In vitro human lung cell culture models to study the toxic potential of nanoparticles. In: Sahu, Saura C; Casciano, Daniel A (eds.) Nanotoxicity (pp. 379-395). Chichester: John Wiley & Sons Ltd. 10.1002/9780470747803.ch19

2008

Muhlfeld, C; Rothen-Rutishauser, B; Blank, F; Vanhecke, D; Ochs, M; Gehr, P (2008). Interactions of nanoparticles with pulmonary structures and cellular responses. American journal of physiology - lung cellular and molecular physiology, 294(5), L817-L829. Bethesda, Md.: American Physiological Society 10.1152/ajplung.00442.2007

Rothen-Rutishauser, Barbara; Mueller, Loretta; Blank, Fabian; Brandenberger, Christina; Muehlfeld, Christian; Gehr, Peter (2008). A newly developed in vitro model of the human epithelial airway barrier to study the toxic potential of nanoparticles. ALTEX - Alternativen zu Tierexperimenten, 25(3), pp. 191-6. Heidelberg: Spektrum Akademischer Verlag

Helfenstein, Maria; Miragoli, Michele; Rohr, Stephan; Müller, Loretta; Wick, Peter; Mohr, Martin; Gehr, Peter; Rothen-Rutishauser, Barbara (2008). Effects of combustion-derived ultrafine particles and manufactured nanoparticles on heart cells in vitro. Toxicology, 253(1-3), pp. 70-8. Amsterdam: Elsevier 10.1016/j.tox.2008.08.018

Clift, Martin J D; Rothen-Rutishauser, Barbara; Brown, David M; Duffin, Rodger; Donaldson, Ken; Proudfoot, Lorna; Guy, Keith; Stone, Vicki (2008). The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line. Toxicology and Applied Pharmacology, 232(3), pp. 418-27. Amsterdam: Elsevier 10.1016/j.taap.2008.06.009

Rothen-Rutishauser, Barbara; Blank, Fabian; Mühlfeld, Christian; Gehr, Peter (2008). In vitro models of the human epithelial airway barrier to study the toxic potential of particulate matter. Expert opinion on drug metabolism & toxicology, 4(8), pp. 1075-89. London: Taylor & Francis 10.1517/17425250802233638

Mühlfeld, Christian; Gehr, Peter; Rothen-Rutishauser, Barbara (2008). Translocation and cellular entering mechanisms of nanoparticles in the respiratory tract. Swiss medical weekly, 138(27-28), pp. 387-91. Muttenz: EMH Schweizerischer Ärzteverlag

Ganapathipillai, Suganthini S; Medová, Michaela; Aebersold, Daniel M; Manley, Paul W; Berthou, Sylvie; Streit, Bruno; Blank-Liss, Wieslawa; Greiner, Richard H; Rothen-Rutishauser, Barbara; Zimmer, Yitzhak (2008). Coupling of mutated Met variants to DNA repair via Abl and Rad51. Cancer research, 68(14), pp. 5769-77. Birmingham, Ala.: American Association for Cancer Research AACR 10.1158/0008-5472.CAN-08-1269

Blank, F; von Garnier, Ch; Obregon, C; Rothen-Rutishauser, B; Gehr, P; Nicod, L (2008). The role of dendritic cells in the Lung: What do we know from in vitro models, animal models and human studies? Expert review of respiratory medicine, 2(2), pp. 215-233. London: Expert Reviews

Mühlfeld, Christian; Müller, Loretta Lina; Gehr, Peter; Rothen-Rutishauser, Barbara (2008). Health effects of inhaled particulate matter. In: Mayer, Andreas (ed.) Particle Filter Retrofit for All Diesel Engines (pp. 17-25). Renningen: Expert

2007

Mühlfeld, Christian; Mayhew, Terry M; Gehr, Peter; Rothen-Rutishauser, Barbara (2007). A novel quantitative method for analyzing the distributions of nanoparticles between different tissue and intracellular compartments. Journal of aerosol medicine - deposition, clearance, and effects in the lung, 20(4), pp. 395-407. New York, N.Y.: Mary Ann Liebert 10.1089/jam.2007.0624

Mühlfeld, Christian; Rothen-Rutishauser, Barbara; Vanhecke, Dimitri; Blank, Fabian; Gehr, Peter; Ochs, Matthias (2007). Visualization and quantitative analysis of nanoparticles in the respiratory tract by transmission electron microscopy. Particle and fibre toxicology, 4, p. 11. London: BioMed Central 10.1186/1743-8977-4-11

Rothen-Rutishauser, Barbara; Mühlfeld, Christian; Blank, Fabian; Musso, Claudia; Gehr, Peter (2007). Translocation of particles and inflammatory responses after exposure to fine particles and nanoparticles in an epithelial airway model. Particle and fibre toxicology, 4, p. 9. London: BioMed Central 10.1186/1743-8977-4-9

Mühlfeld, Christian; Geiser, Marianne; Kapp, Nadine; Gehr, Peter; Rothen-Rutishauser, Barbara (2007). Re-evaluation of pulmonary titanium dioxide nanoparticle distribution using the "relative deposition index": Evidence for clearance through microvasculature. Particle and fibre toxicology, 4, p. 7. London: BioMed Central 10.1186/1743-8977-4-7

Blank, Fabian; Rothen-Rutishauser, Barbara; Gehr, Peter (2007). Dendritic cells and macrophages form a transepithelial network against foreign particulate antigens. American journal of respiratory cell and molecular biology, 36(6), pp. 669-77. New York, N.Y.: American Lung Association 10.1165/rcmb.2006-0234OC

Marquis, Julien; Meyer, Kathrin; Angehrn, Larissa; Kämpfer, Sacha; Rothen-Rutishauser, Barbara; Schümperli, Daniel (2007). Spinal muscular atrophy: SMN2 pre-mRNA splicing corrected by a U7 snRNA derivative carrying a splicing enhancer sequence. Molecular therapy, 15(8), pp. 1479-1486. New York, N.Y.: Nature Publishing Group 10.1038/sj.mt.6300200

Rothen-Rutishauser, B; Schurch, S; Gehr, P (2007). Interaction of particles with membranes. In: (pp. 139-160). Boca Raton: CRC Press

2006

Shaw, Sidney G; Boden, Jane P; Biecker, Erwin; Reichen, Juerg; Rothen, Barbara (2006). Endothelin antagonism prevents diabetic retinopathy in NOD mice: a potential role of the angiogenic factor adrenomedullin. Experimental biology and medicine, 231(6), pp. 1101-5. Maywood, N.J.: Society for Experimental Biology & Medicine

Geiser, Marianne; Rothen-Rutishauser, B; Kapp, N; Schürch, S; Kreyling, W; Schulz, H; Semmler, M; Im Hof, V; Heyder, J; Gehr, P (2006). Respond: Ultrafine particles. Environmental health perspectives(114), A211-A213. Research Triangle Park, N.C.: National Institute of Environmental Health Sciences

Peters, Annette; Veronesi, Bellina; Calderón-Garcidueñas, Lilian; Gehr, Peter; Chen, Lung Chi; Geiser, Marianne; Reed, William; Rothen-Rutishauser, Barbara; Schürch, Samuel; Schulz, Holger (2006). Translocation and potential neurological effects of fine and ultrafine particles a critical update. Particle and fibre toxicology, 3, p. 13. London: BioMed Central 10.1186/1743-8977-3-13

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