Treatment for outpatients with comorbid schizophrenia and substance use disorders: a review

De Witte, Nele A.J.; Crunelle, Cleo L.; Sabbe, Bernard; Moggi, Franz; Dom, Geert (2014). Treatment for outpatients with comorbid schizophrenia and substance use disorders: a review. European addiction research, 20(3), pp. 105-114. Karger 10.1159/000355267

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Aims: This review provides evidence of which interventions need to be part of effective outpatient integrated treatment for patients with comorbid schizophrenia and substance use disorders. Methods: A total of 14 randomized controlled trials were included. Effect sizes are provided to assess the magnitude of the treatments’ efficacy. Results: Despite the studies’ heterogeneity, we can conclude that certain programs (e.g., Behavioral Treatment for Substance Abuse in Schizophrenia) and specific interventions (e.g., motivational interviewing, family interventions) seem to be effective. Moreover, programs integrating multiple interventions are more likely to be positively related to better outcomes than single interventions. Finally, the lack of difference between effect sizes of assertive community treatment compared to case management suggests that a lower caseload is not necessary for positive treatment outcomes. Conclusion: Integrated treatment seems advantageous, although effect sizes are mostly modest. More homogeneous and qualitative sound studies are needed.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Management

UniBE Contributor:

Moggi, Franz

Subjects:

100 Philosophy > 150 Psychology
600 Technology > 610 Medicine & health

ISSN:

1022-6877

Publisher:

Karger

Language:

English

Submitter:

Franz Moggi

Date Deposited:

22 Aug 2014 07:44

Last Modified:

10 Sep 2017 16:19

Publisher DOI:

10.1159/000355267

PubMed ID:

24192558

Uncontrolled Keywords:

dual disorder, schizophrenia, substance use disorder, randomized controlled trial, efficacy

BORIS DOI:

10.7892/boris.53425

URI:

https://boris.unibe.ch/id/eprint/53425

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