De Witte, Nele A.J.; Crunelle, Cleo L.; Sabbe, Bernard; Moggi, Franz; Dom, Geert (2014). Treatment for outpatients with comorbid schizophrenia and substance use disorders: a review. European addiction research, 20(3), pp. 105-114. Karger 10.1159/000355267
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De Witte et al. EAR 2014.pdf - Published Version Available under License Publisher holds Copyright. Download (110kB) | Preview |
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De Witte et al. EAR in press-1.pdf - Accepted Version Available under License Publisher holds Copyright. This is the peer-reviewed but unedited manuscript version of the article. The final, published version is available at http://www.karger.com/?doi=10.1159/000355267 Download (144kB) | Preview |
Aims: This review provides evidence of which interventions need to be part of effective outpatient integrated treatment for patients with comorbid schizophrenia and substance use disorders. Methods: A total of 14 randomized controlled trials were included. Effect sizes are provided to assess the magnitude of the treatments’ efficacy. Results: Despite the studies’ heterogeneity, we can conclude that certain programs (e.g., Behavioral Treatment for Substance Abuse in Schizophrenia) and specific interventions (e.g., motivational interviewing, family interventions) seem to be effective. Moreover, programs integrating multiple interventions are more likely to be positively related to better outcomes than single interventions. Finally, the lack of difference between effect sizes of assertive community treatment compared to case management suggests that a lower caseload is not necessary for positive treatment outcomes. Conclusion: Integrated treatment seems advantageous, although effect sizes are mostly modest. More homogeneous and qualitative sound studies are needed.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Management |
UniBE Contributor: |
Moggi, Franz (A) |
Subjects: |
100 Philosophy > 150 Psychology 600 Technology > 610 Medicine & health |
ISSN: |
1022-6877 |
Publisher: |
Karger |
Language: |
English |
Submitter: |
Franz Moggi |
Date Deposited: |
22 Aug 2014 07:44 |
Last Modified: |
21 Jun 2023 15:03 |
Publisher DOI: |
10.1159/000355267 |
PubMed ID: |
24192558 |
Uncontrolled Keywords: |
dual disorder, schizophrenia, substance use disorder, randomized controlled trial, efficacy |
BORIS DOI: |
10.7892/boris.53425 |
URI: |
https://boris.unibe.ch/id/eprint/53425 |
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