Fleischmann, A; Huland, H; Mirlacher, M; Wilczak, W; Simon, R; Erbersdobler, A; Sauter, G; Schlomm, T (2012). Prognostic relevance of Bcl-2 overexpression in surgically treated prostate cancer is not caused by increased copy number or translocation of the gene. Prostate, 72(9), pp. 991-7. Hoboken, N.J.: Wiley-Blackwell 10.1002/pros.21504
Full text not available from this repository.Overexpression of anti-apoptotic Bcl-2 plays a role in prostate cancer progression, particularly in transformation to androgen-independent disease. Androgen-independent prostate cancers have been shown to harbor Bcl-2 gene copy number gains frequently suggesting that this genetic alteration might play a role in Bcl-2 overexpression. The relation of Bcl-2 overexpression and copy number gains or translocation of the BCL-2 gene in prostate cancer under hormone-naïve conditions is unknown.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology |
UniBE Contributor: |
Fleischmann, Achim |
ISSN: |
0270-4137 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:18 |
Last Modified: |
05 Dec 2022 14:04 |
Publisher DOI: |
10.1002/pros.21504 |
PubMed ID: |
22024950 |
Web of Science ID: |
000303918300008 |
URI: |
https://boris.unibe.ch/id/eprint/5476 (FactScience: 210223) |
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