miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner

Bandi, Nora; Vassella, Erik (2011). miR-34a and miR-15a/16 are co-regulated in non-small cell lung cancer and control cell cycle progression in a synergistic and Rb-dependent manner. Molecular cancer, 10, p. 55. London: BioMed Central 10.1186/1476-4598-10-55

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microRNAs (miRNAs) are small non-coding RNAs that are frequently involved in carcinogenesis. Although many miRNAs form part of integrated networks, little information is available how they interact with each other to control cellular processes. miR-34a and miR-15a/16 are functionally related; they share common targets and control similar processes including G1-S cell cycle progression and apoptosis. The aim of this study was to investigate the combined action of miR-34a and miR-15a/16 in non-small cell lung cancer (NSCLC) cells.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Bandi Hess, Nora and Vassella, Erik

ISSN:

1476-4598

Publisher:

BioMed Central

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:18

Last Modified:

31 Dec 2014 07:33

Publisher DOI:

10.1186/1476-4598-10-55

PubMed ID:

21575235

Web of Science ID:

000291991100001

BORIS DOI:

10.7892/boris.5488

URI:

https://boris.unibe.ch/id/eprint/5488 (FactScience: 210235)

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