IRF4 regulates IL-17A promoter activity and controls ROR?t-dependent Th17 colitis in vivo

Mudter, Jonas; Yu, Jingling; Zufferey, Christel; Brüstle, Anne; Wirtz, Stefan; Weigmann, Benno; Hoffman, Arthur; Schenk, Mirjam; Galle, Peter R; Lehr, Hans A; Mueller, Christoph; Lohoff, Michael; Neurath, Markus F (2011). IRF4 regulates IL-17A promoter activity and controls ROR?t-dependent Th17 colitis in vivo. Inflammatory bowel diseases, 17(6), pp. 1343-1358. Hagerstown, Md.: Lippincott Williams & Wilkins 10.1002/ibd.21476

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The transcription factor IRF4 is involved in several T-cell-dependent chronic inflammatory diseases. To elucidate the mechanisms for pathological cytokine production in colitis, we addressed the role of the IRF transcription factors in human inflammatory bowel disease (IBD) and experimental colitis.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute of Pathology > Immunopathology
04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Schenk, Mirjam and Müller, Christoph

ISSN:

1078-0998

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Christa Hagert

Date Deposited:

04 Oct 2013 14:18

Last Modified:

27 Jul 2017 12:48

Publisher DOI:

10.1002/ibd.21476

PubMed ID:

21305677

Web of Science ID:

000290442400034

URI:

https://boris.unibe.ch/id/eprint/5524 (FactScience: 210277)

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