High-quality lung fixation by controlled closed loop perfusion for stereological analysis in a large animal model

Trachsel, Sebastien; Purkabiri, Kurosch; Loup, Ophelie; Jenni, Hansjörg; Eberle, Balthasar; Ochs, Matthias; Kadner, Alexander (2011). High-quality lung fixation by controlled closed loop perfusion for stereological analysis in a large animal model. Journal of surgical research, 166(2), e97-102. New York, N.Y.: Elsevier 10.1016/j.jss.2010.12.003

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Stereology is an essential method for quantitative analysis of lung structure. Adequate fixation is a prerequisite for stereological analysis to avoid bias in pulmonary tissue, dimensions and structural details. We present a technique for in situ fixation of large animal lungs for stereological analysis, based on closed loop perfusion fixation.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic and Policlinic for Anaesthesiology and Pain Therapy
04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiovascular Surgery

UniBE Contributor:

Trachsel, Sébastien; Eberle, Balthasar and Kadner, Alexander

ISSN:

0022-4804

Publisher:

Elsevier

Language:

English

Submitter:

Jeannie Wurz

Date Deposited:

04 Oct 2013 14:19

Last Modified:

23 Jan 2018 12:16

Publisher DOI:

10.1016/j.jss.2010.12.003

PubMed ID:

21276978

Web of Science ID:

000288168300001

URI:

https://boris.unibe.ch/id/eprint/6082 (FactScience: 210977)

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