High-quality lung fixation by controlled closed loop perfusion for stereological analysis in a large animal model

Trachsel, Sebastien; Purkabiri, Kurosch; Loup, Ophelie; Jenni, Hansjörg; Eberle, Balthasar; Ochs, Matthias; Kadner, Alexander (2011). High-quality lung fixation by controlled closed loop perfusion for stereological analysis in a large animal model. Journal of surgical research, 166(2), e97-102. New York, N.Y.: Elsevier 10.1016/j.jss.2010.12.003

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Stereology is an essential method for quantitative analysis of lung structure. Adequate fixation is a prerequisite for stereological analysis to avoid bias in pulmonary tissue, dimensions and structural details. We present a technique for in situ fixation of large animal lungs for stereological analysis, based on closed loop perfusion fixation.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic and Policlinic for Anaesthesiology and Pain Therapy 04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Heart Surgery
UniBE Contributor:	Trachsel, Sébastien, Eberle, Balthasar, Kadner, Alexander
ISSN:	0022-4804
Publisher:	Elsevier
Language:	English
Submitter:	Jeannie Wurz
Date Deposited:	04 Oct 2013 14:19
Last Modified:	27 Feb 2024 14:29
Publisher DOI:	10.1016/j.jss.2010.12.003
PubMed ID:	21276978
Web of Science ID:	000288168300001
URI:	https://boris.unibe.ch/id/eprint/6082 (FactScience: 210977)