Neurotologic and functional MRI findings in a patient with bilateral profound deafness having Brown-Vialetto-Van Leare syndrome

Salmina, Cinzia; Wagner, Franca; Wiest, Roland; Federspiel, Andrea; Senn, Pascal; Caversaccio, Marco; Vibert-Mennet, Dominique (2014). Neurotologic and functional MRI findings in a patient with bilateral profound deafness having Brown-Vialetto-Van Leare syndrome. Otology & neurotology, 35(9), pp. 1495-1500. Lippincott Williams & Wilkins 10.1097/MAO.0000000000000572

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INTRODUCTION We report the first findings of functional magnetic resonance imaging of the auditory cortex in a young woman with a bilateral cochleovestibular deficit as first manifestation of Brown-Vialetto-Van Leare syndrome. The patient had no open speech discrimination, even with hearing aids, and is depending on lip reading for communication. METHODS To evaluate the possible efficiency of a cochlear implantation, we investigated hemodynamic responses within the central auditory pathways using an auditory functional magnetic resonance imaging paradigm. RESULTS Blood oxygen level-dependent correlates were detected bilaterally along the auditory pathways after exposure to intermittent clicking tone stimulation at 2 kHz. CONCLUSION These results suggest integrity of the central auditory pathways and represent a positive argument to propose a cochlear implantation with the aim to restore hearing.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT)
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Psychiatric Neurophysiology (discontinued)
04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology
04 Faculty of Medicine > University Psychiatric Services

UniBE Contributor:

Salmina, Cinzia; Wagner, Franca; Wiest, Roland; Federspiel, Andrea; Senn, Pascal; Caversaccio, Marco and Vibert-Mennet, Dominique

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1531-7129

Publisher:

Lippincott Williams & Wilkins

Language:

English

Submitter:

Andrea Federspiel

Date Deposited:

05 Jan 2015 13:57

Last Modified:

24 Nov 2015 11:17

Publisher DOI:

10.1097/MAO.0000000000000572

PubMed ID:

25203559

BORIS DOI:

10.7892/boris.61250

URI:

https://boris.unibe.ch/id/eprint/61250

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