Salmina, Cinzia; Wagner, Franca; Wiest, Roland; Federspiel, Andrea; Senn, Pascal; Caversaccio, Marco; Vibert-Mennet, Dominique (2014). Neurotologic and functional MRI findings in a patient with bilateral profound deafness having Brown-Vialetto-Van Leare syndrome. Otology & neurotology, 35(9), pp. 1495-1500. Lippincott Williams & Wilkins 10.1097/MAO.0000000000000572
|
Text
00129492-201410000-00001.pdf - Published Version Available under License Publisher holds Copyright. Download (3MB) | Preview |
INTRODUCTION
We report the first findings of functional magnetic resonance imaging of the auditory cortex in a young woman with a bilateral cochleovestibular deficit as first manifestation of Brown-Vialetto-Van Leare syndrome. The patient had no open speech discrimination, even with hearing aids, and is depending on lip reading for communication.
METHODS
To evaluate the possible efficiency of a cochlear implantation, we investigated hemodynamic responses within the central auditory pathways using an auditory functional magnetic resonance imaging paradigm.
RESULTS
Blood oxygen level-dependent correlates were detected bilaterally along the auditory pathways after exposure to intermittent clicking tone stimulation at 2 kHz.
CONCLUSION
These results suggest integrity of the central auditory pathways and represent a positive argument to propose a cochlear implantation with the aim to restore hearing.