Marbacher, Serge; Fathi, Ali Reza; Muroi, Carl; Coluccia, Daniel; Andereggen, Lukas; Neuschmelting, Volker; Widmer, Hans Rudolf; Jakob, Stephan M.; Fandino, Javier (2015). The rabbit blood shunt subarachnoid haemorrhage model. Acta neurochirurgica - supplementa, 120, pp. 337-342. Springer 10.1007/978-3-319-04981-6_58
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The recently introduced rabbit blood shunt subarachnoid haemorrhage model is based on the two standard procedures of subclavian artery cannulation and transcutaneous cisterna magna puncture. An extracorporeal shunt placed in between the arterial system and the subarachnoid space allows examiner-independent SAH in a closed cranium. Despite its straightforwardness, it is worth examining some specific features and characteristics of the model. We outline technical considerations to successfully perform the model with minimal mortality and morbidity. In addition, we discuss outcome measures, advantages and limitations, and the applicability of the model for the study of early brain injury and delayed cerebral vasospasm after SAH.
Item Type: |
Journal Article (Review Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Intensive Care, Emergency Medicine and Anaesthesiology (DINA) > Clinic of Intensive Care 04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery 04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > Forschungsbereich Mu50 > Forschungsgruppe Neurochirurgie |
UniBE Contributor: |
Coluccia, Daniel, Andereggen, Lukas, Widmer, Hans Rudolf, Jakob, Stephan |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0065-1419 |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Alessandra Angelini |
Date Deposited: |
16 Feb 2015 10:59 |
Last Modified: |
05 Dec 2022 14:39 |
Publisher DOI: |
10.1007/978-3-319-04981-6_58 |
PubMed ID: |
25366648 |
BORIS DOI: |
10.48350/62794 |
URI: |
https://boris.unibe.ch/id/eprint/62794 |
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