Yang, Sara Hsin-Yi; McCalmont, Timothy H; Ahn, George G; Yeh, Iwei (2014). Supraorbital cutaneous fetal rhabdomyoma of intermediate type: a case report. American journal of dermatopathology, 36(5), e93-e96. Lippincott Williams & Wilkins 10.1097/01.dad.0000441941.83273.c5
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A 7-year-old boy was presented with a long-standing slowly growing mass of the left supraorbital area. A biopsy specimen revealed a bland spindle cell proliferation with scattered polygonal cells with acidophilic cytoplasm and cross-striations. Our differential diagnosis included rhabdomyoma of fetal type, leiomyoma with trapping of regenerating skeletal muscle elements, and rhabdomyomatous mesenchymal hamartoma of the skin. Immunohistochemistry demonstrated strong positivity of myoglobin and desmin as well as negativity of caldesmon, suggesting skeletal muscle lineage. The excisional specimen confirmed our diagnosis of cutaneous fetal rhabdomyoma of intermediate type. Additional immunostaining performed on the excisional specimen showed strong Wilms Tumor 1 but only a very faint and focal p63 expression.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology |
UniBE Contributor: |
Yang, Sara Hsin-Yi |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
0193-1091 |
Publisher: |
Lippincott Williams & Wilkins |
Language: |
English |
Submitter: |
Doris Haefelin |
Date Deposited: |
23 Feb 2015 13:50 |
Last Modified: |
05 Dec 2022 14:41 |
Publisher DOI: |
10.1097/01.dad.0000441941.83273.c5 |
PubMed ID: |
24803069 |
BORIS DOI: |
10.7892/boris.63613 |
URI: |
https://boris.unibe.ch/id/eprint/63613 |
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