Ribosome-associated ncRNAs: An emerging class of translation regulators

Pircher, Andreas; Gebetsberger, Jennifer Viktoria; Polacek, Norbert (2014). Ribosome-associated ncRNAs: An emerging class of translation regulators. RNA biology, 11(11), pp. 1335-1339. Taylor and Francis 10.1080/15476286.2014.996459

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Accumulating recent evidence identified the ribosome as binding target for numerous small and long non-protein-coding RNAs (ncRNAs) in various organisms of all 3 domains of life. Therefore it appears that ribosome-associated ncRNAs (rancRNAs) are a prevalent, yet poorly understood class of cellular transcripts. Since rancRNAs are associated with the arguable most central enzyme of the cell it seems plausible to propose a role in translation control. Indeed first experimental evidence on small rancRNAs has been presented, linking ribosome association with fine-tuning the rate of protein biosynthesis in a stress-dependent manner.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Departement of Chemistry and Biochemistry

UniBE Contributor:

Pircher, Andreas; Gebetsberger, Jennifer Viktoria and Polacek, Norbert

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 540 Chemistry

ISSN:

1555-8584

Publisher:

Taylor and Francis

Language:

English

Submitter:

Christina Schüpbach

Date Deposited:

16 Mar 2015 11:56

Last Modified:

10 Sep 2017 12:13

Publisher DOI:

10.1080/15476286.2014.996459

PubMed ID:

25692232

Uncontrolled Keywords:

lncRNA non-coding, RNA ribosome translation control

BORIS DOI:

10.7892/boris.64652

URI:

https://boris.unibe.ch/id/eprint/64652

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