Bone apposition to a titanium-zirconium alloy implant, as compared to two other titanium-containing implants

Saulacic, Nikola; Bosshardt, Dieter; Bornstein, Michael; Berner, Simon; Buser, Daniel (2012). Bone apposition to a titanium-zirconium alloy implant, as compared to two other titanium-containing implants. European cells & materials eCM, 23, pp. 273-286. Aberystwyth (UK): University of Wales

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Implants made of commercially pure titanium (cpTi) are widely and successfully used in dentistry. For certain indications, diameter-reduced Ti alloy implants with improved mechanical strength are highly desirable. The aim was to compare the osseointegration of titanium-zirconium (TiZr) and cpTi implants with a modified sandblasted and acid-etched (SLActive) surface and with a Ti6Al4V alloy that was sand-blasted and acid-washed. Cylindrical implants with two, 0.75 mm deep, circumferential grooves were placed in the maxilla of miniature pigs and allowed to heal for 1, 2, 4 and 8 weeks. Undecalcified toluidine blue-stained ground sections were produced. Surface topography, area fraction of tissue components, and bone-to-implant contact (BIC) were determined. All materials showed significantly different surface roughness parameters. The amount of new bone within the implant grooves increased over time, without significant differences between materials. However, BIC values were significantly related to the implant material and the healing period. For TiZr and cpTi implants, the BIC increased over time, reaching values of 59.38 % and 76.15 % after 2 weeks, and 74.50 % and 84.67 % after 8 weeks, respectively. In contrast, the BIC for Ti6Al4V implants peaked with 42.29 % after 2 weeks followed by a decline to 28.60 % at 8 weeks. Significantly more surface was covered by multinucleated giant cells on Ti6Al4V implants after 4 and 8 weeks. In conclusion, TiZr and cpTi implants showed faster osseointegration than Ti6Al4V implants. Both chemistry and surface topography might have influenced the results. The use of diameter-reduced TiZr implants in more challenging clinical situations warrants further documentation in long-term clinical studies.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > School of Dental Medicine > Department of Periodontology
04 Faculty of Medicine > School of Dental Medicine > Department of Oral Surgery and Stomatology
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Craniomaxillofacial Surgery

UniBE Contributor:

Saulacic, Nikola; Bosshardt, Dieter; Bornstein, Michael and Buser, Daniel

Subjects:

600 Technology > 610 Medicine & health

ISSN:

1473-2262

Publisher:

University of Wales

Language:

English

Submitter:

Eveline Carmen Schuler

Date Deposited:

04 Oct 2013 14:20

Last Modified:

16 Jul 2018 13:03

PubMed ID:

22492019

Web of Science ID:

000307554200021

BORIS DOI:

10.7892/boris.6672

URI:

https://boris.unibe.ch/id/eprint/6672 (FactScience: 211675)

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