Metrics of the normal anterior sclera: imaging with optical coherence tomography

Ebneter, Andreas; Häner, Nathanael; Zinkernagel, Martin (2015). Metrics of the normal anterior sclera: imaging with optical coherence tomography. Graefe's archive for clinical and experimental ophthalmology, 253(9), pp. 1575-1580. Springer 10.1007/s00417-015-3072-5

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BACKGROUND To investigate anterior scleral thickness in a cohort of healthy subjects using enhanced depth imaging anterior segment optical coherence tomography. METHODS Observational case series. The mean scleral thickness in the inferonasal, inferotemporal, superotemporal, and superonasal quadrant was measured 2 mm from the scleral spur on optical coherence tomography in healthy volunteers. RESULTS Fifty-three eyes of 53 Caucasian patients (25 male and 28 female) with an average age of 48.6 years (range: 18 to 92 years) were analysed. The mean scleral thickness was 571 μm (SD 84 μm) in the inferonasal quadrant, 511 μm (SD 80 μm) in the inferotemporal quadrant, 475 (SD 81 μm) in the superotemporal, and 463 (SD 64 μm) in the superonasal quadrant. The mean scleral thickness was significantly different between quadrants (p < 0.0001, repeated measures one-way ANOVA). The association between average scleral thickness and age was statistically significant (p < 0.0001, Pearson r = 0.704). CONCLUSIONS Enhanced depth imaging optical coherence tomography revealed the detailed anatomy of the anterior sclera and enabled non-invasive measurements of scleral thickness in a non-contact approach. The anterior scleral thickness varies significantly between quadrants, resembling the spiral of Tillaux. An association of increasing scleral thickness with age was found.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology

UniBE Contributor:

Ebneter, Andreas and Zinkernagel, Martin

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0721-832X

Publisher:

Springer

Language:

English

Submitter:

Andreas Ebneter

Date Deposited:

07 Dec 2015 09:28

Last Modified:

10 Jun 2016 07:53

Publisher DOI:

10.1007/s00417-015-3072-5

PubMed ID:

26067393

BORIS DOI:

10.7892/boris.70110

URI:

https://boris.unibe.ch/id/eprint/70110

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