Ebneter, Andreas; Häner, Nathanael; Zinkernagel, Martin (2015). Metrics of the normal anterior sclera: imaging with optical coherence tomography. Graefe's archive for clinical and experimental ophthalmology, 253(9), pp. 1575-1580. Springer 10.1007/s00417-015-3072-5
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BACKGROUND
To investigate anterior scleral thickness in a cohort of healthy subjects using enhanced depth imaging anterior segment optical coherence tomography.
METHODS
Observational case series. The mean scleral thickness in the inferonasal, inferotemporal, superotemporal, and superonasal quadrant was measured 2 mm from the scleral spur on optical coherence tomography in healthy volunteers.
RESULTS
Fifty-three eyes of 53 Caucasian patients (25 male and 28 female) with an average age of 48.6 years (range: 18 to 92 years) were analysed. The mean scleral thickness was 571 μm (SD 84 μm) in the inferonasal quadrant, 511 μm (SD 80 μm) in the inferotemporal quadrant, 475 (SD 81 μm) in the superotemporal, and 463 (SD 64 μm) in the superonasal quadrant. The mean scleral thickness was significantly different between quadrants (p < 0.0001, repeated measures one-way ANOVA). The association between average scleral thickness and age was statistically significant (p < 0.0001, Pearson r = 0.704).
CONCLUSIONS
Enhanced depth imaging optical coherence tomography revealed the detailed anatomy of the anterior sclera and enabled non-invasive measurements of scleral thickness in a non-contact approach. The anterior scleral thickness varies significantly between quadrants, resembling the spiral of Tillaux. An association of increasing scleral thickness with age was found.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ophthalmology |
UniBE Contributor: |
Ebneter, Andreas, Zinkernagel, Martin Sebastian |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0721-832X |
Publisher: |
Springer |
Language: |
English |
Submitter: |
Andreas Ebneter |
Date Deposited: |
07 Dec 2015 09:28 |
Last Modified: |
02 Mar 2023 23:26 |
Publisher DOI: |
10.1007/s00417-015-3072-5 |
PubMed ID: |
26067393 |
BORIS DOI: |
10.7892/boris.70110 |
URI: |
https://boris.unibe.ch/id/eprint/70110 |
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