Stelkens, Rike Bahati; Schmid, Corinne; Seehausen, Ole (2015). Hybrid Breakdown in Cichlid Fish. PLoS ONE, 10(5), e0127207. Public Library of Science 10.1371/journal.pone.0127207
|
Text
Stelkens, Schmid, Seehausen 2015 PLoSOne Hybrid Breakdown in Cichlid Fish.pdf - Published Version Available under License Creative Commons: Attribution (CC-BY). Download (424kB) | Preview |
Studies from a wide diversity of taxa have shown a negative relationship between genetic compatibility and the divergence time of hybridizing genomes. Theory predicts the main breakdown of fitness to happen after the F1 hybrid generation, when heterosis subsides and recessive allelic (Dobzhansky-Muller) incompatibilities are increasingly unmasked. We measured the fitness of F2 hybrids of African haplochromine cichlid fish bred from species pairs spanning several thousand to several million years divergence time. F2 hybrids consistently showed the lowest viability compared to F1 hybrids and non-hybrid crosses (crosses within the grandparental species), in agreement with hybrid breakdown. Especially the short- and long-term survival (2 weeks to 6 months) of F2 hybrids was significantly reduced. Overall, F2 hybrids showed a fitness reduction of 21% compared to F1 hybrids, and a reduction of 43% compared to the grandparental, non-hybrid crosses. We further observed a decrease of F2 hybrid viability with the genetic distance between grandparental lineages, suggesting an important role for negative epistatic interactions in cichlid fish postzygotic isolation. The estimated time window for successful production of F2 hybrids resulting from our data is consistent with the estimated divergence time between the multiple ancestral lineages that presumably hybridized in three major adaptive radiations of African cichlids.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE) > Aquatic Ecology |
UniBE Contributor: |
Stelkens, Rike Bahati, Seehausen, Ole |
Subjects: |
500 Science > 570 Life sciences; biology |
ISSN: |
1932-6203 |
Publisher: |
Public Library of Science |
Language: |
English |
Submitter: |
Marcel Häsler |
Date Deposited: |
22 Jul 2015 11:04 |
Last Modified: |
05 Dec 2022 14:48 |
Publisher DOI: |
10.1371/journal.pone.0127207 |
PubMed ID: |
25996870 |
BORIS DOI: |
10.7892/boris.70403 |
URI: |
https://boris.unibe.ch/id/eprint/70403 |
Actions (login required)
 |
Edit item |