Eosinophilia in Dermatologic Disorders

de Graauw, Elisabeth Louisa; Beltraminelli, Helmut; Simon, Hans-Uwe; Simon, Dagmar (2015). Eosinophilia in Dermatologic Disorders. Immunology and allergy clinics of North America, 35(3), pp. 545-560. Elsevier 10.1016/j.iac.2015.05.005

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Eosinophil infiltration can be observed in skin disorders, such as allergic/immunologic, autoimmune, infectious, and neoplastic diseases. Clinical presentations are variable and include eczematous, papular, urticarial, bullous, nodular, and fibrotic lesions; pruritus is a common symptom in all. In this review, we present representative eosinophilic skin diseases according to their clinical pattern, together with histologic findings and diagnostic procedures. We also discuss the potential roles of eosinophils in the pathogenesis of dermatologic disorder. Current pathogenesis-based diagnostic and therapeutic approaches are outlined.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Dermatology
04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Pharmacology

UniBE Contributor:

de Graauw, Elisabeth Louisa; Beltraminelli, Helmut; Simon, Hans-Uwe and Simon, Dagmar

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0889-8561

Publisher:

Elsevier

Language:

English

Submitter:

Debora Scherrer

Date Deposited:

10 Sep 2015 15:50

Last Modified:

26 May 2016 10:13

Publisher DOI:

10.1016/j.iac.2015.05.005

PubMed ID:

26209899

Uncontrolled Keywords:

Atopic dermatitis, Cutaneous lymphoma, Drug hypersensitivity reaction, Eosinophilic dermatitis, Eosinophils, Hypereosinophilic syndromes

BORIS DOI:

10.7892/boris.71494

URI:

https://boris.unibe.ch/id/eprint/71494

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