Modeling absolute differences in life expectancy with a censored skew-normal regression approach.

Moser, André; Clough, Kerri; Zwahlen, Marcel (2015). Modeling absolute differences in life expectancy with a censored skew-normal regression approach. PeerJ, 3, e1162. PeerJ, Ltd 10.7717/peerj.1162

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Parameter estimates from commonly used multivariable parametric survival regression models do not directly quantify differences in years of life expectancy. Gaussian linear regression models give results in terms of absolute mean differences, but are not appropriate in modeling life expectancy, because in many situations time to death has a negative skewed distribution. A regression approach using a skew-normal distribution would be an alternative to parametric survival models in the modeling of life expectancy, because parameter estimates can be interpreted in terms of survival time differences while allowing for skewness of the distribution. In this paper we show how to use the skew-normal regression so that censored and left-truncated observations are accounted for. With this we model differences in life expectancy using data from the Swiss National Cohort Study and from official life expectancy estimates and compare the results with those derived from commonly used survival regression models. We conclude that a censored skew-normal survival regression approach for left-truncated observations can be used to model differences in life expectancy across covariates of interest.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Social and Preventive Medicine (ISPM)

UniBE Contributor:

Moser, André; Clough, Kerri and Zwahlen, Marcel

Subjects:

600 Technology > 610 Medicine & health
300 Social sciences, sociology & anthropology > 360 Social problems & social services

ISSN:

2167-8359

Publisher:

PeerJ, Ltd

Language:

English

Submitter:

Doris Kopp Heim

Date Deposited:

07 Oct 2015 13:49

Last Modified:

10 Sep 2017 10:58

Publisher DOI:

10.7717/peerj.1162

PubMed ID:

26339544

Uncontrolled Keywords:

Censoring; Left-truncation; Life expectancy; Skew-normal regression; Survival regression

BORIS DOI:

10.7892/boris.72233

URI:

https://boris.unibe.ch/id/eprint/72233

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