From Ribbons to Networks: Hierarchical Organization of DNA-Grafted Supramolecular Polymers

Vyborna, Yuliia; Vybornyi, Mykhailo; Häner, Robert (2015). From Ribbons to Networks: Hierarchical Organization of DNA-Grafted Supramolecular Polymers. Journal of the American Chemical Society, 137(44), pp. 14051-14054. American Chemical Society 10.1021/jacs.5b09889

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DNA-grafted supramolecular polymers (SPs) allow the programmed organization of DNA in a highly regular, one-dimensional array. Oligonucleotides are arranged along the edges of pyrene-based helical polymers. Addition of complementary oligonucleotides triggers the assembly of individual nanoribbons resulting in the development of extended supramolecular networks. Network formation is enabled by cooperative coaxial stacking interactions of terminal GC base pairs. The process is accompanied by structural changes in the pyrene polymer core that can be followed spectroscopically. Network formation is reversible, and disassembly into individual ribbons is realized either via thermal denaturation or by addition of a DNA separator strand.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Departement of Chemistry and Biochemistry

UniBE Contributor:

Vyborna, Yuliia; Vybornyi, Mykhailo and Häner, Robert

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 540 Chemistry

ISSN:

0002-7863

Publisher:

American Chemical Society

Funders:

[4] Swiss National Science Foundation

Language:

English

Submitter:

Robert Häner

Date Deposited:

25 Nov 2015 10:08

Last Modified:

10 Sep 2017 11:46

Publisher DOI:

10.1021/jacs.5b09889

PubMed ID:

26491956

BORIS DOI:

10.7892/boris.72790

URI:

https://boris.unibe.ch/id/eprint/72790

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