Kunz, Rhona Elizabeth; Rohrbach, Helene; Gorgas, Daniela; Gendron, Karine; Henke, Diana; Forterre, Franck (2015). Assessment of Intrathecal Pressure in Chondrodystrophic Dogs With Acute Thoracolumbar Disk Disease. Veterinary surgery, 44(6), pp. 687-693. Wiley-Blackwell 10.1111/j.1532-950X.2014.12319.x
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OBJECTIVES
To assess intrathecal pressure (ITP) in chondrodystrophic dogs with thoracolumbar disk extrusion.
STUDY DESIGN
Prospective cohort study.
ANIMALS
Group 1: 11 chondrodystrophic dogs with thoracolumbar disk extrusion and present deep pain sensation. Group 2 (control): 3 healthy chondrodystrophic laboratory dogs without spinal disease.
METHODS
Diagnosis was based on neurologic signs, magnetic resonance imaging (MRI) findings, and surgical confirmation. Blood pressure was maintained within physiologic range during anesthesia. A standardized surgical procedure was applied to minimize factors that could influence measurement readings. An extended hemilaminectomy was performed and ITP was measured with a fiber optic catheter. The catheter was inserted in the subarachnoid space 1 spinal segment caudal to the level of herniation and its tip was advanced to the site of compression.
RESULTS
Significantly higher ITP occurred in chondrodystrophic dogs with acute thoracolumbar disk disease compared with controls. ITP was not associated with duration of clinical signs, neurologic status, outcome, degree of spinal cord compression, or signal intensity changes as assessed by MRI.
CONCLUSION
Acute thoracolumbar disk disease leads to elevated ITP in chondrodystrophic dogs, which may contribute to increased compression of spinal cord parenchyma.
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