Viral genotype-specific role of PNPLA3, PPARG, MTTP, and IL28B in hepatitis C virus-associated steatosis

Cai, Tao; Dufour, Jean-François; Muellhaupt, Beat; Gerlach, Tilman; Heim, Markus; Moradpour, Darius; Cerny, Andreas; Malinverni, Raffaele; Kaddai, Vincent; Bochud, Murielle; Negro, Francesco; Bochud, Pierre-Yves; Swiss Hepatitis C Cohort Study Group, (2011). Viral genotype-specific role of PNPLA3, PPARG, MTTP, and IL28B in hepatitis C virus-associated steatosis. Journal of hepatology, 55(3), pp. 529-35. Amsterdam: Elsevier 10.1016/j.jhep.2010.12.020

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Steatosis is a prominent feature of hepatitis C, especially in patients infected with genotype 3. The analysis of genetic polymorphisms influencing steatosis in chronic hepatitis C has been limited by the studies' small sample size, and important single nucleotide polymorphisms (SNPs), such as those in the patatin-like phospholipase family 3 protein (PNPLA3), were never evaluated.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology

UniBE Contributor:

Dufour, Jean-François

ISSN:

0168-8278

Publisher:

Elsevier

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:22

Last Modified:

05 Dec 2022 14:06

Publisher DOI:

10.1016/j.jhep.2010.12.020

PubMed ID:

21236304

Web of Science ID:

000293930600007

URI:

https://boris.unibe.ch/id/eprint/7721 (FactScience: 213047)

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