Role of integrins in fibrosing liver diseases

Patsenker, Eleonora; Stickel, Felix (2011). Role of integrins in fibrosing liver diseases. American journal of physiology - gastrointestinal and liver physiology, 301(3), G425-34. Bethesda, Md.: American Physiological Society 10.1152/ajpgi.00050.2011

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Integrins and other cell adhesion molecules regulate numerous physiological and pathological mechanisms by mediating the interaction between cells and their extracellular environment. Although the significance of integrins in the evolution and progression of certain cancers is well recognized, their involvement in nonmalignant processes, such as organ fibrosis or inflammation, is only beginning to emerge. However, accumulating evidence points to an instrumental role of integrin-mediated signaling in a variety of chronic and acute noncancerous diseases, particularly of the liver.

Item Type:	Journal Article (Further Contribution)
Division/Institute:	04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology
UniBE Contributor:	Stickel, Felix
ISSN:	0193-1857
Publisher:	American Physiological Society
Language:	English
Submitter:	Factscience Import
Date Deposited:	04 Oct 2013 14:22
Last Modified:	05 Dec 2022 14:06
Publisher DOI:	10.1152/ajpgi.00050.2011
PubMed ID:	21659620
Web of Science ID:	000294328200002
URI:	https://boris.unibe.ch/id/eprint/7726 (FactScience: 213052)