Role of integrins in fibrosing liver diseases

Patsenker, Eleonora; Stickel, Felix (2011). Role of integrins in fibrosing liver diseases. American journal of physiology - gastrointestinal and liver physiology, 301(3), G425-34. Bethesda, Md.: American Physiological Society 10.1152/ajpgi.00050.2011

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Integrins and other cell adhesion molecules regulate numerous physiological and pathological mechanisms by mediating the interaction between cells and their extracellular environment. Although the significance of integrins in the evolution and progression of certain cancers is well recognized, their involvement in nonmalignant processes, such as organ fibrosis or inflammation, is only beginning to emerge. However, accumulating evidence points to an instrumental role of integrin-mediated signaling in a variety of chronic and acute noncancerous diseases, particularly of the liver.

Item Type:

Journal Article (Further Contribution)

Division/Institute:

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology

UniBE Contributor:

Stickel, Felix

ISSN:

0193-1857

Publisher:

American Physiological Society

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:22

Last Modified:

06 Dec 2013 13:28

Publisher DOI:

10.1152/ajpgi.00050.2011

PubMed ID:

21659620

Web of Science ID:

000294328200002

URI:

https://boris.unibe.ch/id/eprint/7726 (FactScience: 213052)

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