Gäbele, Erwin; Dostert, Karin; Dorn, Christoph; Patsenker, Eleonora; Stickel, Felix; Hellerbrand, Claus (2011). A new model of interactive effects of alcohol and high-fat diet on hepatic fibrosis. Alcoholism: clinical and experimental research, 35(7), pp. 1361-7. Oxford: Wiley-Blackwell 10.1111/j.1530-0277.2011.01472.x
Full text not available from this repository.Alcoholic steatohepatitis (ASH) and nonalcoholic steatohepatitis (NASH) are the most frequent conditions leading to elevated liver enzymes and liver cirrhosis, respectively, in the Western world. However, despite strong epidemiological evidence for combined effects on the progression of liver injury, the mutual interaction of the pathophysiological mechanisms is incompletely understood. The aim of this study was to establish and analyze an experimental murine model, where we combined chronic alcohol administration with a NASH-inducing high-fat (HF) diet.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Hepatology |
UniBE Contributor: |
Stickel, Felix |
ISSN: |
0145-6008 |
Publisher: |
Wiley-Blackwell |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:22 |
Last Modified: |
05 Dec 2022 14:06 |
Publisher DOI: |
10.1111/j.1530-0277.2011.01472.x |
PubMed ID: |
21463337 |
Web of Science ID: |
000292109500020 |
URI: |
https://boris.unibe.ch/id/eprint/7727 (FactScience: 213053) |
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