Rapid Recurrence of a Benign Meningial Perineurioma.

Andereggen, Lukas; Vajtai, Istvan; Widmer, Hans Rudolf; Raabe, Andreas; Andres, Robert (2015). Rapid Recurrence of a Benign Meningial Perineurioma. World neurosurgery, 84(6), 2074.e1-2074.e3. Elsevier 10.1016/j.wneu.2015.06.001

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BACKGROUND We describe a rare case of a rapidly recurring benign meningial-based perineurioma. Clinical, radiologic, and pathologic features of a rapidly recurring falxial perineurioma are described; the perineurioma was discovered incidentally in an 86-year-old woman. CASE DESCRIPTION Due to progressive gait disturbances and radiologically proven progression after a 3-year symptom-free interval, subtotal resection of a large falxial-based meningeal tumor was performed. CONCLUSIONS The pathologic examination confirmed the diagnosis of a perineurioma (World Health Organization grade I). Follow-up magnetic resonance tomography 5 months later due to neurologic deterioration revealed an abnormally rapidly growing and extensive local tumor recurrence. Due to the mass effect, reoperation was performed and adjuvant radiation of 20 Gy to the tumor bed was implemented thereafter. Meningeal-based perineuriomas of the central nervous system are extremely rare, and literature on proper management is scarce. Although histologic classification reveals a benign lesion, follow-up may be considered for this type of tumor.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Neurosurgery
04 Faculty of Medicine > Service Sector > Institute of Pathology

UniBE Contributor:

Andereggen, Lukas; Vajtai, Istvan; Widmer, Hans Rudolf; Raabe, Andreas and Andres, Robert

Subjects:

600 Technology > 610 Medicine & health
500 Science > 570 Life sciences; biology

ISSN:

1878-8750

Publisher:

Elsevier

Language:

English

Submitter:

Nicole Söll

Date Deposited:

22 Mar 2016 17:40

Last Modified:

22 Mar 2016 17:40

Publisher DOI:

10.1016/j.wneu.2015.06.001

PubMed ID:

26072455

Uncontrolled Keywords:

Meningeal-based tumor; Perineurioma; Recurrence

BORIS DOI:

10.7892/boris.80141

URI:

https://boris.unibe.ch/id/eprint/80141

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