Multiple drug hypersensitivity: normal Treg cell function but enhanced in vivo activation of drug-specific T cells

Daubner, B; Groux-Keller, M; Hausmann, O V; Kawabata, T; Naisbitt, D J; Park, B K; Wendland, T; Lerch, M; Pichler, W J (2012). Multiple drug hypersensitivity: normal Treg cell function but enhanced in vivo activation of drug-specific T cells. Allergy, 67(1), pp. 58-66. Oxford: Wiley-Blackwell 10.1111/j.1398-9995.2011.02720.x

Full text not available from this repository. (Request a copy)

Up to 10% of patients with severe immune-mediated drug hypersensitivity reactions have tendencies to develop multiple drug hypersensitivities (MDH). The reason why certain individuals develop MDH and the underlying pathomechanism are unclear. We investigated different T cell subpopulations in MDH patients and compared them with patients allergic to a single drug and with healthy controls (HC).

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology, Clinical Immunology and Allergology
04 Faculty of Medicine > Department of General Internal Medicine (DAIM) > Clinic of General Internal Medicine > Centre of Competence for General Internal Medicine

UniBE Contributor:

Hausmann, Oliver; Wendland, Thomas and Pichler, Werner Joseph

ISSN:

0105-4538

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:23

Last Modified:

06 Dec 2013 13:29

Publisher DOI:

10.1111/j.1398-9995.2011.02720.x

PubMed ID:

21933197

Web of Science ID:

000297921100010

URI:

https://boris.unibe.ch/id/eprint/8019 (FactScience: 213433)

Actions (login required)

Edit item Edit item
Provide Feedback