Kouyos, Roger D; von Wyl, Viktor; Yerly, Sabine; Böni, Jürg; Rieder, Philip; Joos, Beda; Taffé, Patrick; Shah, Cyril; Bürgisser, Philippe; Klimkait, Thomas; Weber, Rainer; Hirschel, Bernard; Cavassini, Matthias; Rauch, Andri; Battegay, Manuel; Vernazza, Pietro L; Bernasconi, Enos; Ledergerber, Bruno; Bonhoeffer, Sebastian; Günthard, Huldrych F; ... (2011). Ambiguous nucleotide calls from population-based sequencing of HIV-1 are a marker for viral diversity and the age of infection. Clinical infectious diseases, 52(4), pp. 532-9. Cary, N.C.: Oxford University Press 10.1093/cid/ciq164
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The time passed since the infection of a human immunodeficiency virus (HIV)-infected individual (the age of infection) is an important but often only poorly known quantity. We assessed whether the fraction of ambiguous nucleotides obtained from bulk sequencing as done for genotypic resistance testing can serve as a proxy of this parameter.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology |
UniBE Contributor: |
Rauch, Andri |
ISSN: |
1058-4838 |
Publisher: |
Oxford University Press |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:24 |
Last Modified: |
05 Dec 2022 14:07 |
Publisher DOI: |
10.1093/cid/ciq164 |
PubMed ID: |
21220770 |
Web of Science ID: |
000286677800020 |
BORIS DOI: |
10.7892/boris.8273 |
URI: |
https://boris.unibe.ch/id/eprint/8273 (FactScience: 213789) |
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