Intraoperative image-guided navigation system: development and applicability in 65 patients undergoing liver surgery

Banz Wüthrich, Vanessa; Müller, Philip; Tinguely, Pascale Marie-Pia; Inderbitzin, Daniel; Ribes, Delphine; Peterhans, Matthias; Candinas, Daniel; Weber, Stefan (2016). Intraoperative image-guided navigation system: development and applicability in 65 patients undergoing liver surgery. Langenbeck's archives of surgery, 401(4), pp. 495-502. Springer 10.1007/s00423-016-1417-0

[img] Text
art%3A10.1007%2Fs00423-016-1417-0.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (3MB) | Request a copy

Background Image-guided systems have recently been introduced for their application in liver surgery.We aimed to identify and propose suitable indications for image-guided navigation systems in the domain of open oncologic liver surgery and,more specifically, in the setting of liver resection with and without microwave ablation. Method Retrospective analysis was conducted in patients undergoing liver resection with and without microwave ablation using an intraoperative image-guided stereotactic system during three stages of technological development (accuracy: 8.4 ± 4.4 mm in phase I and 8.4 ± 6.5 mm in phase II versus 4.5 ± 3.6 mm in phase III). It was evaluated, in which indications image-guided surgery was used according to the different stages of technical development. Results Between 2009 and 2013, 65 patients underwent image-guided surgical treatment, resection alone (n=38), ablation alone (n =11), or a combination thereof (n =16). With increasing accuracy of the system, image guidance was progressively used for atypical resections and combined microwave ablation and resection instead of formal liver resection (p<0.0001). Conclusion Clinical application of image guidance is feasible, while its efficacy is subject to accuracy. The concept of image guidance has been shown to be increasingly efficient for selected indications in liver surgery. While accuracy of available technology is increasing pertaining to technological advancements, more and more previously untreatable scenarios such as multiple small, bilobar lesions and so-called vanishing lesions come within reach.

Item Type:

Journal Article (Original Article)

Division/Institute:

10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research > ARTORG Center - Image Guided Therapy
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Viszeralchirurgie
04 Faculty of Medicine > Pre-clinic Human Medicine > BioMedical Research (DBMR) > DBMR Forschung Mu35 > Forschungsgruppe Viszeralchirurgie

04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine > Visceral Surgery
10 Strategic Research Centers > ARTORG Center for Biomedical Engineering Research
04 Faculty of Medicine > Department of Gastro-intestinal, Liver and Lung Disorders (DMLL) > Clinic of Visceral Surgery and Medicine

UniBE Contributor:

Banz Wüthrich, Vanessa; Müller, Philip; Tinguely, Pascale Marie-Pia; Inderbitzin, Daniel; Ribes, Delphine; Peterhans, Matthias; Candinas, Daniel and Weber, Stefan

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health

ISSN:

1435-2443

Publisher:

Springer

Language:

English

Submitter:

Lilian Karin Smith-Wirth

Date Deposited:

13 Jul 2016 14:55

Last Modified:

13 Jul 2016 23:11

Publisher DOI:

10.1007/s00423-016-1417-0

PubMed ID:

27122364

Uncontrolled Keywords:

Image guidance; Intraoperative navigation; Liver ablation; Liver surgery

BORIS DOI:

10.7892/boris.82798

URI:

https://boris.unibe.ch/id/eprint/82798

Actions (login required)

Edit item Edit item
Provide Feedback