Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis

de Souza, Fladjule Rejane Soares; Fontes, Fabrícia Lima; da Silva, Thayse Azevedo; Coutinho, Leonam Gomes; Leib, Stephen L.; Agnez-Lima, Lucymara Fassarella (2011). Association of kynurenine aminotransferase II gene C401T polymorphism with immune response in patients with meningitis. BMC medical genetics, 12(51), p. 51. London: BioMed Central 10.1186/1471-2350-12-51

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The kynurenine (KYN) pathway has been shown to be altered in several diseases which compromise the central nervous system (CNS) including infectious diseases such as bacterial meningitis (BM). The aim of this study was to assess single nucleotide polymorphisms (SNPs) in four genes of KYN pathway in patients with meningitis and their correlation with markers of immune response in BM.

Item Type:

Journal Article (Original Article)

Division/Institute:

04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases

UniBE Contributor:

Leib, Stephen

ISSN:

1471-2350

Publisher:

BioMed Central

Language:

English

Submitter:

Factscience Import

Date Deposited:

04 Oct 2013 14:24

Last Modified:

08 Jun 2016 10:26

Publisher DOI:

10.1186/1471-2350-12-51

PubMed ID:

21473761

Web of Science ID:

000289972400001

BORIS DOI:

10.7892/boris.8287

URI:

https://boris.unibe.ch/id/eprint/8287 (FactScience: 213804)

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