Sensitive and rapid detection of ganciclovir resistance by PCR based MALDI-TOF analysis

Zürcher, Samuel; Mooser, Catherine; Lüthi, Alexander Urs; Mühlemann, Kathrin; Barbani, Maria Teresa; Mohacsi, Paul; Garzoni, Christian; Gorgievski-Hrisoho, Meri; Schaller, André; Flatz, Lukas (2012). Sensitive and rapid detection of ganciclovir resistance by PCR based MALDI-TOF analysis. Journal of clinical virology, 54(4), pp. 359-63. Amsterdam: Elsevier 10.1016/j.jcv.2012.04.019

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Cytomegalovirus (CMV) infection is associated with significant morbidity and mortality in transplant recipients. Resistance against ganciclovir is increasingly observed. According to current guidelines, direct drug resistance testing is not always performed due to high costs and work effort, even when resistance is suspected.

Item Type:	Journal Article (Original Article)
Division/Institute:	04 Faculty of Medicine > Service Sector > Institute for Infectious Diseases 04 Faculty of Medicine > Department of Cardiovascular Disorders (DHGE) > Clinic of Cardiology 04 Faculty of Medicine > Department of Haematology, Oncology, Infectious Diseases, Laboratory Medicine and Hospital Pharmacy (DOLS) > Clinic of Infectiology 04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
UniBE Contributor:	Zürcher, Samuel, Mooser, Catherine, Lüthi, Alexander, Mühlemann, Kathrin, Barbani, Maria Teresa, Mohacsi, Paul, Garzoni, Christian, Gorgievski, Meri, Schaller, André
ISSN:	1386-6532
ISBN:	1386-6532
Publisher:	Elsevier
Language:	English
Submitter:	Anette van Dorland
Date Deposited:	04 Oct 2013 14:24
Last Modified:	05 Dec 2022 14:07
Publisher DOI:	10.1016/j.jcv.2012.04.019
PubMed ID:	22633201
Web of Science ID:	000306374700015
Additional Information:	Zuercher, Samuel Mooser, Catherine Luethi, Alexander Urs Muehlemann, Kathrin Barbani, Maria Teresa Mohacsi, Paul Garzoni, Christian Gorgievski-Hrisoho, Meri Schaller, Andre Flatz, Lukas
URI:	https://boris.unibe.ch/id/eprint/8318 (FactScience: 213837)