McCormack, Mark; Alfirevic, Ana; Bourgeois, Stephane; Farrell, John J; Kasperavičiūtė, Dalia; Carrington, Mary; Sills, Graeme J; Marson, Tony; Jia, Xiaoming; de Bakker, Paul I W; Chinthapalli, Krishna; Molokhia, Mariam; Johnson, Michael R; O'Connor, Gerard D; Chaila, Elijah; Alhusaini, Saud; Shianna, Kevin V; Radtke, Rodney A; Heinzen, Erin L; Walley, Nicole; ... (2011). HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans. New England journal of medicine NEJM, 364(12), pp. 1134-43. Waltham, Mass.: Massachusetts Medical Society MMS 10.1056/NEJMoa1013297
Full text not available from this repository.Carbamazepine causes various forms of hypersensitivity reactions, ranging from maculopapular exanthema to severe blistering reactions. The HLA-B*1502 allele has been shown to be strongly correlated with carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) in the Han Chinese and other Asian populations but not in European populations.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > Department of Dermatology, Urology, Rheumatology, Nephrology, Osteoporosis (DURN) > Clinic of Rheumatology and Immunology |
UniBE Contributor: |
Pichler, Werner Joseph |
ISSN: |
0028-4793 |
Publisher: |
Massachusetts Medical Society MMS |
Language: |
English |
Submitter: |
Factscience Import |
Date Deposited: |
04 Oct 2013 14:26 |
Last Modified: |
05 Dec 2022 14:07 |
Publisher DOI: |
10.1056/NEJMoa1013297 |
PubMed ID: |
21428769 |
Web of Science ID: |
000288701100008 |
URI: |
https://boris.unibe.ch/id/eprint/9317 (FactScience: 215015) |
Actions (login required)
 |
Edit item |