Determination of fluoroquinolone antibiotic residues in the plasma of Eurasian griffon vultures (Gyps fulvus) in Spain

Casa-Díaz, Encarna; Cristòfol, Carles; Cuenca, Rafaela; Agustí, Susana; Carneiro, Manuela; Marco, Ignasi; Lavín, Santiago; Margalida, Antoni (2016). Determination of fluoroquinolone antibiotic residues in the plasma of Eurasian griffon vultures (Gyps fulvus) in Spain. Science of the total environment, 557-558, pp. 620-626. Elsevier 10.1016/j.scitotenv.2016.03.083

[img] Text
Casas-Díaz_SciTotEnv2016.pdf - Published Version
Restricted to registered users only
Available under License Publisher holds Copyright.

Download (2MB) | Request a copy

Due to the possible toxicological impact, the accumulation of pharmaceuticals in wildlife as a consequence of human practices is of growing concern. The consumption of carrion at feeding stations – the so-called ‘vulture restaurants’ – with no management of the veterinary drugs it contains may expose scavengers to pharmaceuticals. To demonstrate this, we analyzed plasma from Eurasian griffon vultures (Gyps fulvus) originating from two different areas of Spain for antibiotics such as enrofloxacin and ciprofloxacin, its primary metabolite. Quinolone residues were detected in about 65% (n = 106) of birds, of which 15.1% (16/106) had quantifiable amounts of enrofloxacin (0.049±0.102 μg/mL) and 5.7% (6/106) of ciprofloxacin (0.009±0.007 μg/mL). The differences in exposure between the two sampled areas are attributable to different types of carrion management: the vultures that fed in areas with a high density of dead livestock (supplied directly to feeding stations) were more prone to exposure than those that sought food in areas where carcass availability is more unpredictable. Our findings are evidence that vultures have access to medicated livestock and that there are quantifiable levels of livestock antibiotics in vulture plasma.However, the vultures analyzed in this study had maximumantibiotic concentrations of only 0.4 μg/mL, much less than the concentrations used in the clinical treatment of scavengers and a level that is probably too small to cause intoxication.

Item Type:

Journal Article (Original Article)

Division/Institute:

08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE)
08 Faculty of Science > Department of Biology > Institute of Ecology and Evolution (IEE) > Conservation Biology

UniBE Contributor:

Margalida, Antoni

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 590 Animals (Zoology)

ISSN:

0048-9697

Publisher:

Elsevier

Language:

English

Submitter:

Olivier Roth

Date Deposited:

21 Jun 2017 09:38

Last Modified:

21 Jun 2017 09:38

Publisher DOI:

10.1016/j.scitotenv.2016.03.083

PubMed ID:

27037883

BORIS DOI:

10.7892/boris.93726

URI:

https://boris.unibe.ch/id/eprint/93726

Actions (login required)

Edit item Edit item
Provide Feedback