Quality of life after paediatric ischaemic stroke

Kornfeld, Salome; Studer, Martina; Winkelbeiner, Stephanie; Regényi, Mária; Boltshauser, Eugen; Steinlin, Maja (2017). Quality of life after paediatric ischaemic stroke. Developmental medicine and child neurology, 59(1), pp. 45-51. Blackwell 10.1111/dmcn.13295

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Paediatric arterial ischaemic stroke can lead to reduced quality of life (QoL). It is important to identify predictors of QoL to support recovery. We examined long-term QoL after arterial ischaemic stroke concerning different variables.
Children registered in the Swiss Neuropediatric Stroke Registry and suffering from arterial ischaemic stroke between 2000 and 2008 were included. Two years post-stroke, assessments included intelligence quotient tests for cognitive impairment and modified Rankin Scale (mRS) for neurological impairment; 5 years post-stroke, the Kidscreen-27 was used for QoL, DSM-IV criteria screening was used for attention deficits, and the ABILHAND-Kids was used for manual motor skills. Age at stroke, sex, socioeconomic status, lesion characteristics, neuropsychological and motor outcome, and mRS were correlated with QoL measures.
Seventy children were examined (49 males, 21 females; mean age 7y 2wks). Age at stroke, sex, socioeconomic status, and lesion characteristics did not influence QoL; IQ below average and attention deficits partially influenced QoL. The highest predictive value for QoL was found for manual motor impairment (p=0.002) and mRS scores (p=0.013). Combined motor, cognitive, and attention impairment negatively affected QoL (p=0.001).
Neurological and cognitive impairments after paediatric arterial ischaemic stroke negatively influence QoL. Children with motor and neurological problems, as well as those with combined motor, cognitive, and attention problems, are at higher risk for low QoL.

Item Type:

Journal Article (Original Article)


04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine
04 Faculty of Medicine > Department of Gynaecology, Paediatrics and Endocrinology (DFKE) > Clinic of Paediatric Medicine > Neuropaediatrics

Graduate School:

Swiss Graduate School for Cognition, Learning and Memory (SGS-CLM)
Graduate School for Health Sciences (GHS)

UniBE Contributor:

Kornfeld, Salome, Studer, Martina (A), Regényi, Mária, Boltshauser, Eugen, Steinlin, Maja


600 Technology > 610 Medicine & health
100 Philosophy > 150 Psychology








Anette van Dorland

Date Deposited:

21 Mar 2018 12:36

Last Modified:

29 Mar 2023 23:35

Publisher DOI:


PubMed ID:


Uncontrolled Keywords:

AIS Arterial ischaemic stroke HRQoL Health-related quality of life mRS Modified Rankin Scale P/A Parents/autonomy QoL Quality of life SES Socioeconomic status





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