Precision Medicine in Allergic Disease - Food Allergy, Drug Allergy, and Anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology.

Muraro, Antonella; Lemanske, Robert F; Castells, Mariana; Torres, Maria J; Khan, David; Simon, Hans-Uwe; Bindslev-Jensen, Carsten; Burks, Wesley; Poulsen, Lars K; Sampson, Hugh A; Worm, Margitta; Nadeau, Kari C (2017). Precision Medicine in Allergic Disease - Food Allergy, Drug Allergy, and Anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. Allergy, 72(7), pp. 1006-1021. Wiley-Blackwell 10.1111/all.13132

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This consensus document summarizes the current knowledge on the potential for precision medicine in food allergy, drug allergy and anaphylaxis under the auspices of the PRACTALL collaboration platform. PRACTALL is a joint effort of the European Academy of Allergy and Clinical Immunology (EAACI) and the American Academy of Allergy, Asthma and Immunology (AAAAI), which aims to synchronize the European and American approaches to allergy care. Precision medicine is an emerging approach for disease treatment based on disease endotypes, which are phenotypic subclasses associated with specific mechanisms underlying the disease. Although significant progress has been made in defining endotypes for asthma, definitions of endotypes for food and drug allergy or for anaphylaxis lag behind. Progress has been made in discovery of biomarkers to guide a precision medicine approach to treatment of food and drug allergy, but further validation and quantification of these biomarkers is needed to allow their translation into practice in the clinical management of allergic disease. This article is protected by copyright. All rights reserved.

Item Type:

Journal Article (Review Article)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute of Pharmacology

UniBE Contributor:

Simon, Hans-Uwe

Subjects:

600 Technology > 610 Medicine & health

ISSN:

0105-4538

Publisher:

Wiley-Blackwell

Language:

English

Submitter:

Jana Berger

Date Deposited:

11 Sep 2017 10:26

Last Modified:

01 Aug 2018 02:30

Publisher DOI:

10.1111/all.13132

PubMed ID:

28122115

Uncontrolled Keywords:

allergy anaphylaxis endotype phenotype precision medicine

BORIS DOI:

10.7892/boris.95346

URI:

https://boris.unibe.ch/id/eprint/95346

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