Impact of low inspired oxygen fraction on oxygenation in clinical horses under general anesthesia

Levionnois, Olivier; Zuehlke, N; Kuhn, M; Spadavecchia, Claudia (2016). Impact of low inspired oxygen fraction on oxygenation in clinical horses under general anesthesia. Pferdeheilkunde, 32(5), pp. 461-468. Hippiatrika Verlagsgesellschaft 10.21836/PEM20160507

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The objective was to compare the use of 0.3 and >0.95 oxygen inspired fraction during general anesthesia in horses. Forty
client-owned adult horses were anesthetized in dorsal or in lateral recumbency with isoflurane in oxygen and randomly allocated to receive
inspiratory fraction of oxygen >0.95 (group HIGH) or 0.3 (group LOW). Mechanical ventilation was provided using pressure controlled
mode. Arterial blood gas analysis was performed before, during and after general anesthesia. The group LOW obtained lower intra-operative
PaO2 values but better indices of venous admixture than the group HIGH. The PaO2 further decreased during the recovery, without
significant differences between groups. Even though the use of lower oxygen inspired fraction (0.3) tended to improve pulmonary function
during general anesthesia, it markedly decreased safety as a result of hypoxemia. During the recovery, no difference was observed between
groups for the arterial oxygenation such that lower intra-anesthetic oxygen inspired fraction did not provide any advantages.

Item Type:

Journal Article (Original Article)

Division/Institute:

05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV) > DKV - Anaesthesiology
05 Veterinary Medicine > Department of Clinical Veterinary Medicine (DKV)

UniBE Contributor:

Levionnois, Olivier, Spadavecchia, Claudia

Subjects:

600 Technology > 630 Agriculture
600 Technology > 610 Medicine & health

ISSN:

0177-7726

Publisher:

Hippiatrika Verlagsgesellschaft

Language:

English

Submitter:

Helene Rohrbach Rüegsegger

Date Deposited:

20 Jul 2017 17:26

Last Modified:

17 Apr 2024 16:22

Publisher DOI:

10.21836/PEM20160507

URI:

https://boris.unibe.ch/id/eprint/96114

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