Statistical shape modeling of compound musculoskeletal structures around the thigh region

Chu, Chengwen; Takao, Masaki; Ogawa, Takeshi; Yokota, Futoshi; Sato, Yoshinobu; Zheng, Guoyan (2016). Statistical shape modeling of compound musculoskeletal structures around the thigh region. In: 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI 2016) (pp. 885-888). IEEE 10.1109/ISBI.2016.7493407

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Accurate 3D models of lower extremity are required for model-based simulations in kinematic analysis of musculoskeletal (MS) system. In this paper, we present a modeling framework which combines a hybrid registration scheme with an articulated statistical shape model (aSSM) construction technique. The present modeling framework is used to develop an aSSM of compound MS structures based on a training set of 12 single side CT images with the associated ground-truth segmentation of 7 structures around the thigh region. By incorporating 90% of the training set variations, the model exhibits a generalization ability of 2.77±0.48 mm and specificity of 2.87±0.43 mm. The constructed aSSM has potential applications in model-based 2D-3D construction, 3D medical image segmentation, and kinematic analysis of MS system. To the best of our knowledge, this is the first 3D aSSM of compound MS structures around the thigh region.

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