Localization and Segmentation of 3D Intervertebral Discs from MR Images via a Learning Based Method: A Validation Framework

Chu, Chengwen; Yu, Weimin; Li, Shuo; Zheng, Guoyan (2016). Localization and Segmentation of 3D Intervertebral Discs from MR Images via a Learning Based Method: A Validation Framework. In: 2015 International Workshop on Computational Methods and Clinical Applications for Spine Imaging. Lecture Notes in Computer Science: Vol. 9402 (pp. 141-149). Cham: Springer International Publishing 10.1007/978-3-319-41827-8_14

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In this paper, we present the results of evaluating our fully automatic intervertebral disc (IVD) localization and segmentation method using the training data and the test data provided by the localization and segmentation challenge organizers of the 3rd MICCAI Workshop & Challenge on Computational Methods and Clinical Applications for Spine Imaging - MICCAI–CSI2015. We introduce a validation framework consisting of four standard evaluation criteria to evaluate the performance of our method for both localization and segmentation tasks. More specifically, for localization we propose to use the mean localization distance (MLD) with standard deviation (SD) as well as the successful detection rate with three ranges of accuracy. For segmentation, we propose to use the Dice overlap coefficients (DOC) and average absolute distance (AAD) between the automatic segmented disc surfaces and the associated ground truth. Using the proposed metrics, we first validate our previously introduced approach by conducting a comprehensive leave-one-out experiment on the IVD challenge training data which consists of 15 three-dimensional T2-weighted turbo spin echo magnetic resonance (MR) images and the associated ground truth. For localization, we respectively achieved a successful detection rate of 61, 92, and 93%93% when the accuracy range is set to 2.0, 4.0, and 6.0 mm, and a mean localization error of 1.8±0.91.8±0.9 mm. For segmentation, we obtained a mean DOC of 88%88% and a mean AAD of 1.4 mm. We further evaluated the performance of our approach on the test-1 dataset consisting of five MR images released at the pre-test stage and the test-2 dataset consisting of another five MR images released at the on-site competition stage. The results were obtained with a blind test where the performance evaluations were conducted by the challenge organizers. For localization on the test-1 dataset we achieved a successful detection rate of 91.4, 100.0, and 100.0%100.0% with a MLD ±± SD of 1.0±0.81.0±0.8 mm, and for localization on the test-2 dataset we achieved a successful detection rate of 77.1, 100.0, and 100.0%100.0% with a MLD ±± SD of 1.4±0.71.4±0.7 mm, respectively. For segmentation on the test-1 dataset we obtained a mean DOC of 90%90% and a mean AAD of 1.2 mm, and for segmentation on the test-2 dataset we obtained a mean DOC of 92%92% and a mean AAD of 1.3 mm, respectively.

Item Type:

Book Section (Book Chapter)

Division/Institute:

04 Faculty of Medicine > Pre-clinic Human Medicine > Institute for Surgical Technology & Biomechanics ISTB

Graduate School:

Graduate School for Cellular and Biomedical Sciences (GCB)

UniBE Contributor:

Chu, Chengwen; Yu, Weimin and Zheng, Guoyan

Subjects:

500 Science > 570 Life sciences; biology
600 Technology > 610 Medicine & health
600 Technology > 620 Engineering

ISBN:

978-3-319-41826-1

Series:

Lecture Notes in Computer Science

Publisher:

Springer International Publishing

Language:

English

Submitter:

Guoyan Zheng

Date Deposited:

24 May 2017 14:20

Last Modified:

24 May 2017 14:20

Publisher DOI:

10.1007/978-3-319-41827-8_14

URI:

https://boris.unibe.ch/id/eprint/97787

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