Anschütz, Lukas Peter; Buchwalder, Melanie; Dettmer, Matthias; Caversaccio, Marco; Wagner, Franca (2017). A Clinical and Radiological Approach to the Management of Benign Mesenchymal Sinonasal Tumors. ORL, 79(3), pp. 131-146. Karger 10.1159/000468945
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PURPOSE
Benign mesenchymal sinonasal neoplasms (BMSN) are rare and histologically heterogeneous. Differential diagnosis, appropriate management, and outcome are still a matter of debate. The aim of this study is to provide evidence for further refinement of assessment and treatment in the future.
PROCEDURES
We retrospectively reviewed data on 93 patients with neuroradiologically verified BMSN treated at our university reference center during the past 22 years.
RESULTS
The most frequent BMSN recorded in our cohort was osteoma of the frontal sinus. Only one-third of the patients affected were symptomatic at initial presentation. The 2 other common fibro-osseous tumor entities, fibrous dysplasia and ossifying fibroma, were confirmed in 12 and 6 patients, respectively. Patients with soft tissue tumor entities such as hemangioma, glomangiopericytoma, angiofibroma, and hamartoma were all symptomatic and underwent surgical resection.
CONCLUSION
Understanding and recognizing the spectrum of appearances of benign mesenchymal sinonasal tumors will improve patient assessment and clinical management. The pathognomonic neuroradiological signs of a particular tumor entity should be actively sought as the neuroradiological features may be the diagnostic clues. Computed tomography and magnetic resonance imaging play complementary roles in identifying the morphological details and locoregional staging of benign mesenchymal sinonasal tumors.
Item Type: |
Journal Article (Original Article) |
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Division/Institute: |
04 Faculty of Medicine > Service Sector > Institute of Pathology > Clinical Pathology 04 Faculty of Medicine > Service Sector > Institute of Pathology 04 Faculty of Medicine > Department of Head Organs and Neurology (DKNS) > Clinic of Ear, Nose and Throat Disorders (ENT) 04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology |
UniBE Contributor: |
Anschütz, Lukas Peter, Dettmer, Matthias, Caversaccio, Marco, Wagner, Franca |
Subjects: |
500 Science > 570 Life sciences; biology 600 Technology > 610 Medicine & health |
ISSN: |
1423-0275 |
Publisher: |
Karger |
Language: |
English |
Submitter: |
Martin Zbinden |
Date Deposited: |
08 Aug 2017 08:20 |
Last Modified: |
05 Dec 2022 15:05 |
Publisher DOI: |
10.1159/000468945 |
PubMed ID: |
28391267 |
BORIS DOI: |
10.7892/boris.99470 |
URI: |
https://boris.unibe.ch/id/eprint/99470 |