Current knowledge of miRNAs as biomarkers in Breast Cancer.

Gasparri, Maria Luisa; Besharat, Zein Mersini; Besharat, Raad Aris; Ruscito, Ilary; Nirgianakis, Konstantinos; Farooqi, Ammad Ahmad; Papadia, Andrea; Ferretti, Elisabetta; Benedetti Panici, Pierluigi; Mueller, Michael David (2018). Current knowledge of miRNAs as biomarkers in Breast Cancer. In: Fayyaz, Sundas; Farooqi, Ammad Ahmad (eds.) Recent Trends in Cancer Biology: Spotlight on Signaling Cascades and microRNAs (pp. 221-231). Springer 10.1007/978-3-319-71553-7_12

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Cancer is a multifaceted disease and overwhelmingly increasing experimental evidence has helped us to develop a deeper understanding of the role of signal transduction cascades in cancer development and progression. Tissue microarrays and next generation sequencing technologies have assisted us to gather missing pieces of jigsaw puzzle and we now know that deregulation of spatio-temporally controlled signaling cascades play fundamental role in metastasis and resistance against wide ranging therapeutics.

This book offers a balanced overview of the rapidly emerging cutting edge research in molecular oncology and good source of knowledge for established oncologists, basic and medical students and pharmaceutical industry associated R&D departments.

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