Cantisani, Andrea; Stegmayer, Katharina; Federspiel, Andrea; Bohlhalter, Stephan; Wiest, Roland; Walther, Sebastian (2018). Blood perfusion in left inferior and middle frontal gyrus predicts communication skills in schizophrenia. Psychiatry research: Neuroimaging, 274, pp. 7-10. Elsevier 10.1016/j.pscychresns.2018.02.002
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Schizophrenia is one of the most debilitating mental disorders, severely affecting patients' community functioning. Functional capacity (FC) describes the skills necessary for successful functional outcome (FO), such as financial knowledge or communication skills. We investigated whether resting-state cerebral blood flow (rCBF) measured at baseline with arterial spin labeling (ASL) would predict FC or FO at a 6-months follow-up in 27 schizophrenia patients. A negative linear association was noted between FC and rCBF in the left inferior and middle frontal gyrus, areas involved in language processing, suggesting a potential relationship between cerebral perfusion and prospective FC in schizophrenia.
Item Type: |
Journal Article (Original Article) |
|---|---|
Division/Institute: |
04 Faculty of Medicine > University Psychiatric Services > University Hospital of Psychiatry and Psychotherapy > Translational Research Center 04 Faculty of Medicine > Department of Radiology, Neuroradiology and Nuclear Medicine (DRNN) > Institute of Diagnostic and Interventional Neuroradiology |
UniBE Contributor: |
Cantisani, Andrea, Stegmayer, Katharina Deborah Lena, Federspiel, Andrea, Wiest, Roland Gerhard Rudi, Walther, Sebastian |
Subjects: |
600 Technology > 610 Medicine & health |
ISSN: |
0925-4927 |
Publisher: |
Elsevier |
Language: |
English |
Submitter: |
Martin Zbinden |
Date Deposited: |
23 Apr 2018 09:16 |
Last Modified: |
02 Mar 2023 23:30 |
Publisher DOI: |
10.1016/j.pscychresns.2018.02.002 |
PubMed ID: |
29456122 |
Uncontrolled Keywords: |
Arterial spin labeling Functional capacity Functional outcome Resting-state cerebral blood flow Schizophrenia |
BORIS DOI: |
10.7892/boris.112075 |
URI: |
https://boris.unibe.ch/id/eprint/112075 |
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