DNA-Modified Vesicles – Self-Assembly and Functionalization

Bürki, Nutcha; Langenegger, Simon Matthias; Häner, Robert (7 September 2018). DNA-Modified Vesicles – Self-Assembly and Functionalization (Unpublished). In: Swiss Chemical Society Fall Meeting 2018. 07.09.2018.

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We previously showed that 2,7-disubstituted phosphodiester-linked phenanthrene trimers self-assemble into tubular structures in aqueous medium.[1] Further it was shown that phenanthrene oligomers conjugated to DNA assemble into vesicles.[2] The DNA-phenanthrene conjugates presented here were also found to assemble into vesicular objects. Their morphology depends on the salt concentration and annealing conditions.
The formed DNA-modified vesicles are investigated for functionalization by hybridization with Au nanoparticle-modified oligonucleotides. The vesicles were characterized by atomic force microscopy (AFM) and transmission electron microscopy (TEM).

Item Type:

Conference or Workshop Item (Poster)

Division/Institute:

08 Faculty of Science > Department of Chemistry, Biochemistry and Pharmaceutical Sciences (DCBP)

UniBE Contributor:

Bürki, Nutcha, Langenegger, Simon Matthias, Häner, Robert

Subjects:

500 Science > 570 Life sciences; biology
500 Science > 540 Chemistry

Language:

English

Submitter:

Nutcha Bürki

Date Deposited:

20 Sep 2018 08:15

Last Modified:

05 Dec 2022 15:18

BORIS DOI:

10.7892/boris.120019

URI:

https://boris.unibe.ch/id/eprint/120019

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